Evidence map›Paper›PMID 42422848›Full record

ArticleFrontiers in medicine2026

Bridging the theory-practice gap in laboratory medicine: development and application of a standardized case library for fostering clinical reasoning in postgraduate training.

Qin Wang, Jingjing Zhang, Hao Zhang, Aihua Wang, Yuanyuan Wu, Zhi Duan, Zhidong Chen, Tingdong Zhou, Yu Wei, Wenwen Chu and 1 more

Abstract read
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Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Qin WangDepartment of Clinical Laboratory, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Jingjing ZhangDepartment of Geriatric Cardiology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Hao ZhangDepartment of Clinical Laboratory, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Aihua WangDepartment of Clinical Laboratory, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Yuanyuan WuDepartment of Clinical Laboratory, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Zhi DuanDepartment of Clinical Laboratory, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Zhidong ChenDepartment of Clinical Laboratory, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Tingdong ZhouDepartment of Clinical Laboratory, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Yu WeiDepartment of Clinical Laboratory, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Wenwen ChuDepartment of Clinical Laboratory, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Qiang ZhouDepartment of Clinical Laboratory, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Case-based learning (CBL) is crucial for developing clinical reasoning in medical education. However, its application in clinical laboratory diagnostics is hindered by the absence of standardized, real-world teaching cases. This study aimed to develop a comprehensive teaching case library and conduct an exploratory evaluation of its potential associations with student outcomes. Methods: This study employed a two-phase, quasi-experimental, non-randomized design with a historical control. In the first phase, a standardized case library was constructed using real patient data from a tertiary hospital's Laboratory and Hospital Information Systems, following principles of systematic coverage and clinical relevance. All 28 cases, spanning six laboratory subspecialties, underwent dual review by laboratory medicine specialists and clinicians. In the second phase, this library was integrated into a structured, closed-loop CBL curriculum. A total of 36 professional master's degree students in Clinical Laboratory Diagnostics were included. The historical control group ( Results: The library comprises 28 peer-reviewed cases. Compared to the historical control group, the CBL group showed higher engagement levels: instructor ratings showed that 66.6% of CBL students achieved "high engagement" (score ≥ 4 on a 5-point scale) versus 33.3% in the control group; student self-reported mean composite engagement score was 4.5 ± 0.4 in the CBL group compared to 3.2 ± 0.6 in the control group ( Conclusion: A systematically constructed and closed-loop implemented case library, integrated with CBL, appears to offer a promising approach for bridging the theory-practice gap and supporting the development of essential clinical competencies. These preliminary, hypothesis-generating findings from a single-center, quasi-experimental study should be interpreted as exploratory rather than confirmatory, and they warrant validation in larger-scale, preferably randomized, investigations. This scalable educational model offers a practical framework for laboratory medicine training and holds potential for improving interprofessional collaboration.

Indexed as

case-based learningclinical laboratory diagnosticsclinical thinkingpostgraduate educationteaching case library

Identifiers

PMID42422848
PMCPMC13342040

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.