Evidence map›Paper›PMID 42422846›Full record

ArticleFrontiers in medicine2026

A clinical nomogram incorporating hyperhomocysteinemia for predicting severe delayed encephalopathy after acute carbon monoxide poisoning: a retrospective single-center study.

Wanqiu Zhu, Yi Zhang, Fang Liang, Shuhua Yuan, Yu Gao, Xuehua Liu, Xiaomin Hou, Linlin Ma, Jing Zhang, Ding Nan and 3 more

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In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Wanqiu ZhuDepartment of Hyperbaric Oxygen, Beijing Chao-Yang Hospital (Changying Campus), Capital Medical University, Beijing, China.
Yi ZhangDepartment of Hyperbaric Oxygen, Beijing Chao-Yang Hospital (Changying Campus), Capital Medical University, Beijing, China.
Fang LiangDepartment of Hyperbaric Oxygen, Beijing Chao-Yang Hospital (Changying Campus), Capital Medical University, Beijing, China.
Shuhua YuanDepartment of Hyperbaric Oxygen, Beijing Chao-Yang Hospital (Changying Campus), Capital Medical University, Beijing, China.
Yu GaoDepartment of Hyperbaric Oxygen, Beijing Chao-Yang Hospital (Changying Campus), Capital Medical University, Beijing, China.
Xuehua LiuDepartment of Hyperbaric Oxygen, Beijing Chao-Yang Hospital (Changying Campus), Capital Medical University, Beijing, China.
Xiaomin HouDepartment of Hyperbaric Oxygen, Beijing Chao-Yang Hospital (Changying Campus), Capital Medical University, Beijing, China.
Linlin MaDepartment of Hyperbaric Oxygen, Beijing Chao-Yang Hospital (Changying Campus), Capital Medical University, Beijing, China.
Jing ZhangDepartment of Hyperbaric Oxygen, Beijing Chao-Yang Hospital (Changying Campus), Capital Medical University, Beijing, China.
Ding NanDepartment of Hyperbaric Oxygen, Beijing Chao-Yang Hospital (Changying Campus), Capital Medical University, Beijing, China.
Lu YangDepartment of Hyperbaric Oxygen, Beijing Chao-Yang Hospital (Changying Campus), Capital Medical University, Beijing, China.
Yafei HeDepartment of Hyperbaric Oxygen, Beijing Chao-Yang Hospital (Changying Campus), Capital Medical University, Beijing, China.
Jing YangDepartment of Hyperbaric Oxygen, Beijing Chao-Yang Hospital (Changying Campus), Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Severe delayed encephalopathy after acute carbon monoxide poisoning (s-DEACMP) is a disabling complication associated with substantial long-term neurological impairment, yet reliable predictors for risk stratification during acute hospitalization remain limited. This study aimed to identify predictors associated with s-DEACMP and to develop a preliminary predictive model. Methods: In this retrospective single-center cohort study, 200 patients with acute carbon monoxide poisoning (ACMP) admitted between 2017 and 2024 were analyzed. Patients were categorized into DEACMP ( Results: Patients with s-DEACMP were significantly older and had longer duration of disturbance of consciousness, higher prevalence of hypertension and hyperhomocysteinemia, elevated D-dimer levels, and lower serum albumin concentrations compared with controls (all Conclusion: The proposed nomogram may assist in identifying patients at increased risk for s-DEACMP during acute hospitalization. External multicenter validation is required before broader clinical application.

Indexed as

carbon monoxide poisoningdelayed encephalopathyhyperhomocysteinemiahypertensionnomogrampredictive model

Identifiers

PMID42422846
PMCPMC13342190

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