Evidence map›Paper›PMID 42422815›Full record

ArticleFrontiers in medicine2026

Case Report: Plastic bronchitis temporally associated with bordetella pertussis infection in a vaccinated child.

Haiting Lin, Mingfei Zhong, Yuan Tu, Yueyuan Li

Abstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Haiting Lin *Department of Pediatrics, The People's Hospital of Cenxi City, Wuzhou, Guangxi, China.
Mingfei Zhong *Department of Pediatrics, The People's Hospital of Cenxi City, Wuzhou, Guangxi, China.
Yuan TuDepartment of Pediatrics, The People's Hospital of Cenxi City, Wuzhou, Guangxi, China.
Yueyuan LiDepartment of Pediatrics, The People's Hospital of Cenxi City, Wuzhou, Guangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To describe the clinical presentation, diagnostic process, management, and potential mechanisms of plastic bronchitis (PB) temporally associated with Bordetella pertussis infection in a vaccinated child. Methods: This case report follows the CARE (Case Report) guidelines. We describe the clinical course of a 6-year-old boy with PB complicating lower respiratory tract infection, including clinical features, laboratory findings, imaging, bronchoscopy, bronchoalveolar lavage fluid (BALF) pathogen detection, treatment, and follow-up. Results: The patient presented with a 4-day history of cough and fever without the classical inspiratory "whoop" of pertussis. He had completed routine pertussis immunization. Chest computed tomography (CT) demonstrated right middle lobe atelectasis with bilateral pulmonary inflammation. Despite symptomatic improvement following empirical antimicrobial therapy, atelectasis persisted. Flexible bronchoscopy revealed obstructive mucopurulent airway casts consistent with PB, which were removed. BALF pathogen detection identified Bordetella pertussis and Rhinovirus A as high-confidence pathogens, with Aspergillus fumigatus and Epstein-Barr virus detected at lower confidence levels. After bronchoscopic intervention and pathogen-directed therapy, symptoms resolved completely and imaging confirmed lung re-expansion. No recurrence was observed during 6 months of follow-up. Conclusion: This case reports a potential temporal association between PB and Bordetella pertussis infection in a vaccinated child with atypical clinical features. To our knowledge, this is the first documented case of PB temporally associated with B. pertussis. However, causality cannot be definitively established due to the presence of copathogens and the low sequence count of the bacterium. Early bronchoscopy with BALF analysis should be considered in children with pneumonia complicated by persistent atelectasis or poor response to empirical therapy.

Indexed as

atelectasisbordetella pertussisbronchoscopycase reportplastic bronchitis

Identifiers

PMID42422815
PMCPMC13341915

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