Evidence map›Paper›PMID 42422779›Full record

ArticleNational journal of maxillofacial surgery

Effect of prophylactic antimicrobial therapy in orthodontic tooth extractions: A randomized controlled trial.

Prakhar Mittal, Amiya Agrawal, Arunesh K Tiwari, Akhilesh K Pandey, Vibha Singh, Geeta Singh, Sumit Kumar

Abstract read
In one paragraph

Article in National journal of maxillofacial surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Prakhar Mittal *Intern, King George's Medical University, Lucknow, Uttar Pradesh, India.
Amiya Agrawal *Department of Oral and Maxillofacial Surgery, King George's Medical University, Lucknow, Uttar Pradesh, India.
Arunesh K TiwariDepartment of Oral and Maxillofacial Surgery, King George's Medical University, Lucknow, Uttar Pradesh, India.
Akhilesh K PandeyDepartment of Oral and Maxillofacial Surgery, King George's Medical University, Lucknow, Uttar Pradesh, India.
Vibha SinghDepartment of Oral and Maxillofacial Surgery, King George's Medical University, Lucknow, Uttar Pradesh, India.
Geeta SinghDepartment of Oral and Maxillofacial Surgery, King George's Medical University, Lucknow, Uttar Pradesh, India.
Sumit KumarDepartment of Health Research-Multidisciplinary Research Unit, King George's Medical University, Lucknow, Uttar Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The use of antibiotics postdental extraction is quite prevalent, leading to widespread healthcare crisis, antimicrobial resistance (AMR). Judicious use of these antibiotics can prevent the onset of adverse events and enhance the positive patient outcome. The role of antibiotic therapy in orthodontic extraction of premolars among the healthy cohorts is unclear, requiring due consideration. Materials and Methods: The prospective study explores the role of prophylactic antibiotic in orthodontic extraction of premolar teeth. Forty-four patients were randomly divided into two groups: group A included 23 patients receiving Amoxicillin 500 mg, while group B included 21 patients receiving Lactose capsule (placebo), for 3 days postextraction. Postextraction the patients were evaluated for postoperative wound healing using Landry scale at day 3, day 10, and day 21. Pain scores were evaluated using 100 mm Visual Analog Scale at day 10. Results: This study showed better wound healing in group A (3.74 ± 0.45) compared to group B (3.05 ± 0.22) ( Conclusion: Similar wound healing progression across both the groups along with similar pain control challenges the need for antibiotic therapy in orthodontic extraction of healthy teeth. The rising AMR has led to equivocal increase in opportunist infections, requiring the healthcare professionals to judiciously use the antibiotics.

Indexed as

Antimicrobial resistanceorthodontic extractionprophylactic antibioticswound healing

Identifiers

PMID42422779
PMCPMC13342738

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.