ArticleNational journal of maxillofacial surgery
Effect of intrasocket application of hyaluronic acid on pain, swelling, and trismus after surgical extraction of impacted mandibular third molar - A randomized control trial.
Article in National journal of maxillofacial surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Mandibular third molar removal is one of the most widely performed treatments in the oral cavity. Nevertheless, surgeons often encounter undesirable postoperative sequelae. These inflammatory responses after wisdom teeth surgery may badly affect a patients' quality of life. Though traditional measures such as non-steroidal anti-inflammatory drugs and corticosteroids proposed for control of postoperative complications work well, their potential side effects have led to a search for an easily applicable way to reduce postoperative pain and swelling. Hyaluron or Hyaluronic acid (HA) is a biomaterial that has been introduced as an alternative approach to enhance wound healing. Hyaluronic acid is a major carbohydrate with multifaceted roles. It plays a critical role in wound healing by inducing early granulation tissue formation, inhibiting destructive inflammation, and promoting angiogenesis. It is available in gel or liquid form to be applied topically in oral cavity. This study aims to evaluate the efficacy of hyaluronic acid in reducing pain, swelling, and trismus after surgical extraction of the lower third molar. Materials and Methods: Forty patients underwent surgical extraction of impacted lower third molar for this study A.0.7 mL 2%hyaluronic acid gel (Hyalgun®) along with abgel as scaffold was placed in the extraction socket in study group and abgel alone was placed in control group. Data collection was performed to assess the pain using the visual analog scale on 1 Results: The hyaluronic acid gel group demonstrated statistically significantly less swelling and trismus. Pain assessed on the visual analog scale (VAS) was significantly less ( Conclusion: The application of HA gel following third molar extraction effectively alleviates postoperative pain, swelling, and trismus, enhancing patient comfort and recovery. HA gel, with its anti-inflammatory and analgesic properties, offers promise as an adjunct in postoperative management.
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