Evidence map›Paper›PMID 42422710›Full record

Observational studyFrontiers in public health2026

Temporal trends in refractive error among children and adolescents in Germany - a large-scale analysis of spectacle sales data from dispensing opticians from 2001 to 2025.

Navid Farassat, Sven P Heinrich, Wolf A Lagrèze, Niklas Nagel

Abstract readObservational Study
In one paragraph

Observational study in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Navid FarassatEye Center, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Sven P HeinrichEye Center, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Wolf A LagrèzeEye Center, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Niklas NagelDepartment of Economics, University of Freiburg, Freiburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: While the prevalence of myopia is rising globally, driven primarily by steep increases in East Asia, recent data on refractive trends in Europe suggest a plateau. This study aimed to evaluate temporal trends in refractive error and myopia progression of children and adolescents in Germany over a 25-year period from January 2001 to December 2025. Specifically, we sought to determine whether there is evidence of an accelerating "myopia epidemic" or a recent pandemic-induced myopic shift. Methods: This retrospective observational study analyzed a large-scale dataset of real-world spectacle sales sourced from 490 independent dispensing opticians across Germany. It included ~1,250,000 prescription readings from ~440,000 individuals (~49% female) aged 3 to 18 years at baseline. Refractive error was evaluated as spherical equivalent refraction (SER), with myopia defined as ≤ -0.50 diopters (D). Cross-sectional and longitudinal analyses were conducted to evaluate shifts over time in SER, myopic progression, and the influence of age, sex, urbanization, and socioeconomic status. Results: Contrary to global projections, the overall pediatric spectacle-wearing cohort did not undergo a myopic shift. Instead, a mild hyperopic shift was observed, with the mean SER increasing from +0.05 D in 2001-2005 to +0.53 D in 2021-2025 ( Conclusion: This 25-year large-scale analysis found no evidence of an accelerating myopia epidemic or a pandemic-associated surge in myopia progression among spectacle-wearing children and adolescents in Germany. The mean refractive error and the incidence of myopic prescriptions have remained stable or even exhibited a slight hyperopic shift in recent cohorts, suggesting that regional environmental and lifestyle factors may effectively mitigate global myopization trends in this population.

Indexed as

EyeglassesRefractive ErrorsAdolescentChildChild, PreschoolCross-Sectional StudiesFemaleGermanyHumansMaleMyopiaOpticiansPrevalenceRetrospective Studiesadolescentschildrenepidemiologymyopiarefraction

Identifiers

PMID42422710
PMCPMC13341904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.