Evidence map›Paper›PMID 42422511›Full record

ArticleFrontiers in psychiatry2026

Psychiatry and the unknown future: the period of hope.

Andreas Conca, Giancarlo Giupponi, Klaus Eisendle, Filippo Boschello, Fabian Max Wedmann

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andreas ConcaBolzano Central Hospital, Bolzano, Italy.
Giancarlo GiupponiBolzano Central Hospital, Bolzano, Italy.
Klaus EisendleBolzano Central Hospital, Bolzano, Italy.
Filippo BoschelloBolzano Central Hospital, Bolzano, Italy.
Fabian Max WedmannBolzano Central Hospital, Bolzano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modern psychiatry is transitioning from an entity-based taxonomy toward a systems-oriented science that integrates biological, psychological, social, and existential levels of analysis. We propose a conceptual framework that combines genetics and multi-omics approaches, synergetics, complex systems theory, and a neo-existentialist perspective. Within this framework, psychiatric illness is conceptualized as a crisis of regulation and meaning emerging across dynamically interacting multi-level networks. We discuss implications for clinical practice, including process-based psychotherapy, idiographic mapping, and neuromodulatory interventions, as well as consequences for service design, such as recovery-oriented integrated care ecosystems and ethical challenges in forensic settings. Finally, we outline key research directions, including multimodal clustering approaches and digital phenotyping, aimed at capturing non-linear trajectories of mental suffering and recovery. "In order to possess what you do not possess…" - T.S. Eliot.

Indexed as

complex system theorydigital pheno typingmeaningmulti level networksynergetics

Identifiers

PMID42422511
PMCPMC13343227

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.