Evidence map›Paper›PMID 42422452›Full record

ArticleFrontiers in pediatrics2026

Optimizing discharge outcomes in very preterm infants by a novel integrated family and rehabilitation care model-a retrospective case-matched study.

Ren Zhuxiao, Ren Jianbing, Yi Aiwen, Mo Shisheng, Wang Zhu, Yang Shumei, Yin Shiyao, Nie Chuan

Abstract read
In one paragraph

Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ren Zhuxiao *Department of Neonatology, Guangdong Women and Children Hospital, Southern University of Science and Technology, Guangzhou, China.
Ren Jianbing *Department of Neonatology, Guangdong Women and Children Hospital, Southern University of Science and Technology, Guangzhou, China.
Yi Aiwen *Department of Rehabilitation Medicine, Guangdong Women and Children Hospital, Southern University of Science and Technology, Guangzhou, China.
Mo Shisheng *Department of Neonatology, Guangdong Women and Children Hospital, Southern University of Science and Technology, Guangzhou, China.
Wang Zhu *Department of Neonatology, Guangdong Women and Children Hospital, Southern University of Science and Technology, Guangzhou, China.
Yang ShumeiDepartment of Neonatology, Guangdong Women and Children Hospital, Southern University of Science and Technology, Guangzhou, China.
Yin ShiyaoDepartment of Rehabilitation Medicine, Guangdong Women and Children Hospital, Southern University of Science and Technology, Guangzhou, China.
Nie ChuanDepartment of Neonatology, Guangdong Women and Children Hospital, Southern University of Science and Technology, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In our routine NICU settings, traditionally implemented family-centered care (FCC) often showed limitations including insufficient parental involvement, high caregiver burden, and lack of systematic rehabilitation integration, which restricted improvements in respiratory, feeding, and neurodevelopmental outcomes. This study introduced a novel integrated family-centered care (NIFCC) model combining daytime family-integrated care, bedside rehabilitation, and nighttime professional NICU care, and investigated its effect on discharge outcomes in very preterm infants compared with traditionally implemented FCC in our clinical setting. Methods: A retrospective 1:1 case-matched study was conducted in a level 4 NICU. Fifty-three very preterm infants (gestational age <32 weeks) receiving NIFCC were 1:1 matched with 53 controls under our traditionally implemented family-centered care. Primary outcomes included oxygen weaning, full oral feeding establishment, and Neonatal Behavioral Observation (NBO) scores. Secondary outcomes included complications, anthropometric measures, hospital stay, and costs. Results: The NIFCC group had significantly higher oxygen independence (92.5% vs. 73.6%, Conclusion: The NIFCC model is safe and effective, significantly improving oxygen weaning, oral feeding, neurobehavioral development, and growth in very preterm infants. By addressing the incomplete implementation of traditional FCC caused by insufficient staff training and lack of care culture transformation, NIFCC provides a valuable strategy for optimizing NICU care quality.

Indexed as

case-matched studydischarge outcomesintegrated family and rehabilitation careretrospectivevery preterm infants

Identifiers

PMID42422452
PMCPMC13342056

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.