Evidence map›Paper›PMID 42422305›Full record

ArticleThe British journal of cardiology2025

Acute type A aortic dissection with cerebral malperfusion: diagnosis and repair using a novel technique.

Marina Elias, Abubakar Ibn Sidik, Sergey Garmanov, Vladimir Mironenko, Aliu Moomin

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In one paragraph

Article in The British journal of cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Marina EliasFellow in Cardiothoracic Surgery.
Abubakar Ibn SidikFellow in Cardiothoracic Surgery RUDN University, Miklukho-Maklaya Str 6, 117198, Moscow, Russia.
Sergey GarmanovConsultant in Cardiothoracic Surgery.
Vladimir MironenkoConsultant in Cardiothoracic Surgery A.N. Bakulev National Medical Research Center of Cardiovascular Surgery, Ministry of Health of Russia, Rublyovskoye Shosse, 135, Moscow, Russia.
Aliu MoominResearch Fellow in Cancer Research University of Aberdeen, Rowett Institute, Foresterhill Campus, Aberdeen, AB25 2ZD.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Though a rare condition, acute type A aortic dissection (ATAAD) is associated with high morbidity and mortality; hence, timely diagnosis and surgery are important to reduce the risk of mortality. If the dissection extends into the aortic arch branches, ensuring adequate cerebral perfusion during surgery is crucial to preventing stroke. A 50-year-old man presented to the emergency department with symptoms of acute chest pain, dizziness, and headache. His blood pressure was 180/110 mmHg and heart rate was 100 bpm. He had a high blood pressure and heart rate and was initially treated with glyceryl trinitrate. Initial investigations ruled out acute coronary syndrome. Further investigations revealed ATAAD with the involvement of arch branches, an incomplete (open) circle of Willis and cerebral malperfusion. He was prepared for a branch-first total aortic arch replacement. Due to the high risk of stroke in this patient, off-pump axillo-axillary bypass (adaptive perfusion technique) was used to ensure bihemispheric cerebral perfusion throughout the surgery. The surgery was uneventful, and the patient was discharged 12 days later. Postoperative follow-up at six months was normal. In conclusion, ATAAD is a surgical emergency that can mimic other acute thoracic conditions, such as pulmonary embolism and acute coronary syndrome; therefore, a judicious approach should be applied in the diagnosis and early management of symptoms. The reconstruction technique should be tailored to the patient's needs; as this patient had a poorly functioning circle of Willis and cerebral hypoperfusion, continuous bilateral cerebral perfusion was essential to prevent irreversible cerebral ischaemic insult. The adaptive technique is easy to learn for surgeons who are already proficient in aortic dissection procedures, it is reproducible and requires only minor changes to the surgical setup without any substantial increase in operative time. Adoption of this technique in other surgical centres could be beneficial in increasing the success rate for the treatment of ATAAD.

Indexed as

aortic dissectionbranch-first techniquecerebral adaptive perfusioncerebral malperfusiontotal aortic arch replacement

Identifiers

PMID42422305
PMCPMC13343821

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