Evidence map›Paper›PMID 42422274›Full record

ArticleOxford medical case reports2026

Detection of occult non-mass enhancement in bloody nipple discharge using US/MRI fusion imaging: a case report.

Yukako Mouri, Masayuki Saito, Kanna Ozaki, Hirona Banno, Manami Goto, Mirai Ido, Takahito Ando, Junko Kousaka, Kimihito Fujii, Tsuneo Imai and 4 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxford medical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yukako MouriDepartment of Breast and Endocrine Surgery, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi 480-1195, Japan.ORCID https://orcid.org/0009-0003-1352-003X
Masayuki SaitoDepartment of Breast and Endocrine Surgery, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi 480-1195, Japan.ORCID https://orcid.org/0009-0006-5279-8167
Kanna OzakiDepartment of Breast and Endocrine Surgery, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi 480-1195, Japan.
Hirona BannoDepartment of Breast and Endocrine Surgery, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi 480-1195, Japan.
Manami GotoDepartment of Breast and Endocrine Surgery, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi 480-1195, Japan.
Mirai IdoDepartment of Breast and Endocrine Surgery, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi 480-1195, Japan.
Takahito AndoDepartment of Breast and Endocrine Surgery, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi 480-1195, Japan.
Junko KousakaDepartment of Breast and Endocrine Surgery, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi 480-1195, Japan.
Kimihito FujiiDepartment of Breast and Endocrine Surgery, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi 480-1195, Japan.
Tsuneo ImaiDepartment of Breast and Endocrine Surgery, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi 480-1195, Japan.
Shogo NakanoDepartment of Breast and Endocrine Surgery, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi 480-1195, Japan.
Takanori ItoDepartment of Surgical Pathology, Aichi Medical University, Japan.
Emiko TakahashiDepartment of Surgical Pathology, Aichi Medical University, Japan.
Koujiro SuzukiDepartment of Radiology, Aichi Medical University, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 66-year-old woman presented with right bloody nipple discharge (BND). Initial evaluation, including palpation, mammography (MMG), ultrasonography (US), and cytology, revealed no abnormalities. In the second year, persistent BND prompted breast magnetic resonance imaging (MRI), which demonstrated non-mass enhancement in the lower right breast and was classified as Breast Imaging Reporting and Data System (BI-RADS) category 3; therefore, imaging surveillance was performed. In the third year, cytological examination revealed atypical cells. Repeat MRI again demonstrated non-mass enhancement. US/MRI fusion identified two suspicious regions; however, ultrasound-guided needle biopsy showed no evidence of malignancy. Because of persistent BND and cytological atypia, excisional biopsy was performed, and ductal carcinoma in situ (DCIS) was confirmed. US/MRI fusion may assist in localizing target areas for biopsy in patients with MRI-detected lesions without corresponding findings on MMG or US; however, histopathological confirmation remains essential.

Indexed as

bloody nipple dischargeductal carcinoma in situnon-mass enhancementUS/MRI fusion

Identifiers

PMID42422274
PMCPMC13343778

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.