Evidence map›Paper›PMID 42422198›Full record

ArticleFrontiers in neurology

Comorbidities and impact on quality of life in patients with Ménière's disease: a single-center cross-sectional study.

Zhongbao Zhang, Linna Jiao, Guohua Zhang, Qingfeng Rong, Qiuli Wang, Xiaohui Lu, Qin Wang

Abstract read
In one paragraph

Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhongbao ZhangXiaolan Clinical Institute of Shantou University Medical College, Zhongshan, Guangdong Province, China.
Linna JiaoXiaolan Clinical Institute of Shantou University Medical College, Zhongshan, Guangdong Province, China.
Guohua ZhangXiaolan Clinical Institute of Shantou University Medical College, Zhongshan, Guangdong Province, China.
Qingfeng RongXiaolan Clinical Institute of Shantou University Medical College, Zhongshan, Guangdong Province, China.
Qiuli WangDizziness and Vertigo Treatment Center,Xiaolan People's Hospital of Zhongshan (The Fifth People's Hospital of Zhongshan), Zhongshan, Guangdong Province, China.
Xiaohui LuXiaolan Clinical Institute of Shantou University Medical College, Zhongshan, Guangdong Province, China.
Qin WangXiaolan Clinical Institute of Shantou University Medical College, Zhongshan, Guangdong Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ménière's disease (MD) is a chronic vestibular disorder that significantly impacts patients' quality of life (QoL). However, the influence of comorbid conditions on QoL in MD patients remains inadequately explored. Objective: To investigate the prevalence of comorbidities in patients with MD and analyze their impact on patients' QoL. Methods: A cross-sectional analysis was conducted on 473 MD patients who received treatment in our hospital. Demographic data, comorbidity information, psychological symptoms (assessed by Hospital Anxiety and Depression Scale, HAD) and QoL (evaluated by Ménière's disease Quality of Life Questionnaire, MDoQ) were collected. Spearman correlation analysis was used to explore the relationship between comorbidities and QoL scores, and independent-samples t-test was applied for intergroup comparison. A multiple linear regression analysis was conducted to identify comorbidities influencing MDoQ. Results: The study included 328 females (69.3%) and 145 males (30.7%) with a mean age of 45.6 ± 14.5 years and an average disease duration of 4.5 ± 2.0 years. The most common comorbidities were hypertension (49.0%), sleep disorders (36.6%), and diabetes mellitus (28.8%). Clear anxiety symptoms were observed in 59.2% of subjects, whereas distinct depressive symptoms were detected in 53.9%. The mean MDoQ score was 43.62 ± 12.50 (range: 25-76). Correlation analysis revealed that hypertension ( Conclusion: Comorbidities are highly prevalent in MD patients, with hypertension, sleep disorders and diabetes mellitus being the most common. These comorbidities, together with the high incidence of anxiety and depression, significantly impair patients' QoL. Comprehensive management of MD should include systematic screening, early intervention for common comorbidities and psychological support to improve patients' clinical outcomes and QoL.

Indexed as

anxietycomorbidityhypertensionMDoQMénière’s diseasequality of life

Identifiers

PMID42422198
PMCPMC13341428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.