SynthesisFrontiers in cardiovascular medicine2026
Can resistance training alone or resistance training combined with aerobic training improve arterial stiffness, endothelial function, and other vascular function indicators in adults with hypertension or overweight/obesity-related vascular risk? A systematic review and meta-analysis of randomized controlled trials.
Synthesis in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Exercise in Patients with Subclinical Atherosclerosis: Mechanisms, Clinical Evidence, and Practical Recommendations.Current atherosclerosis reports · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This systematic review and meta-analysis synthesized evidence from randomized controlled trials to examine the overall effects of resistance training alone or in combination with aerobic training on arterial stiffness, endothelial function, and other vascular function indices in adults with hypertension or overweight/obesity-related vascular risk. Methods: Following PRISMA guidelines, PubMed, Embase, Web of Science, the Cochrane Library, Ovid, CNKI, Wanfang Data, VIP, and CBM were searched from inception to January 2026 for randomized controlled trials examining resistance training alone or combined with aerobic training on vascular function in adults with hypertension or overweight/obesity-related vascular risk. Random-effects meta-analyses were performed using Results: Twenty randomized controlled trials were included. Resistance training-based interventions performed alone or combined with aerobic training significantly reduced arterial stiffness ( Conclusions: Resistance training-based interventions may improve selected vascular function outcomes in adults with hypertension or overweight/obesity-related vascular risk, particularly FMD. However, the FMD finding should be interpreted cautiously because of potential publication bias or small-study effects and the limited evidence base. Evidence for arterial stiffness was less robust after sensitivity analyses, no consistent benefit was observed for wave reflection indices, and evidence for peripheral haemodynamics remained insufficient. Current evidence does not support the superiority of resistance training-based interventions performed alone over combined aerobic-resistance training, and exploratory subgroup findings should not be used to infer optimal training prescriptions. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420261335684.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.