ArticleFrontiers in bioengineering and biotechnology2026
Electrospun PLA/chitosan/PEG nanofibers for controlled delivery of ethyl
Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Electrohydrodynamic jet printing of gelatin-GPTMS-PEO hybrid biomaterial inks for high-resolution fibre patterning.Frontiers in bioengineering and biotechnology · 2026Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Electrospun nanofibers have attracted considerable attention as drug delivery platforms due to their high surface area, interconnected porosity, and tunable structure. Ethyl p-methoxycinnamate (EPMC), a bioactive cinnamate derivative from Kaempferia galanga, exhibits anti-inflammatory and antioxidant activities, but its direct application may be limited by poor stability and uncontrolled release behavior. Incorporating EPMC into biodegradable electrospun polymer systems may improve its delivery performance. Methods: In this study, EPMC-loaded poly(lactic acid)/chitosan/polyethylene glycol (PLA/CS/PEG) nanofiber membranes were fabricated by electrospinning. Formulation composition and processing parameters were systematically evaluated. The resulting nanofibers were characterized using scanning electron microscopy, FTIR spectroscopy, contact angle measurement, and mechanical testing. Drug loading efficiency and Results: Stable electrospinning conditions were obtained at 10 wt% PLA, 0.5 wt% chitosan, 1.0 wt% PEG, 20 kV applied voltage, 15 cm tip-to-collector distance, and a feed rate of 1.0 mL h Conclusion: These findings demonstrate that PLA/CS/PEG electrospun nanofibers provide an effective biodegradable carrier for controlled delivery of EPMC. The selected PLA/CS/PEG nanofiber membrane represents a promising biodegradable platform for controlled delivery of bioactive natural compounds such as EPMC.
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