ArticleJournal of medical physics
Bridging Precision and Practice: A Systematic Approach to Total Body Irradiation in Routine Clinical Settings.
Article in Journal of medical physics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To evaluate the feasibility of delivering total body irradiation (TBI) in a standard linear accelerator bunker using a treatment planning system (TPS) and a conventional multileaf collimator assembly. The aim was to address dose homogeneity and lung shielding within practical clinical constraints. Materials and Methods: TBI was performed using conventional anterior-posterior beam delivery, dividing the whole-body irradiation into three to four sections with patients positioned on the treatment couch. Whole-body computed tomography images, acquired with Vac-Loc immobilization, were used for planning in the TPS. The source-to-surface distance was maintained between 120 and 135 cm. The moving-junction technique provided uniformity at section junctions, and the multileaf collimator (MLC) was employed for customized lung shielding. Patient setup and shield positioning were verified with an electronic portal imaging device. Results: The plan resulted in ≥ 92% of the target volume received ≥ 90% of the prescribed dose while V110 remained <7%. The mean lung dose was kept below 8 Gy. The prescribed dose rate at the mid-plane was approximately 1.8 Gy/min. Point dose measurements showed agreement with the TPS calculations within 2%, indicating high dosimetric accuracy and reliable dose delivery. Conclusions: Conventional linac setups, combined with TPS-guided planning, MLC-based lung shielding, and moving-junction delivery approaches, provide a practical solution for TBI with acceptable dose uniformity and lung sparing, supporting implementation in standard radiation oncology practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.