ArticleSurgical case reports2026
Upfront Surgery for c-Stage IIIB Non-Small Cell Lung Cancer with an Abnormally High Preoperative Serum Carcinoembryonic Antigen Level: A Case Report.
Article in Surgical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionCarcinoembryonic antigen (CEA) is one of the most widely used tumor markers in clinical practice. In non-small cell lung cancer, elevated preoperative serum CEA levels have been reported to be associated with a poor prognosis. CASE PRESENTATION: A 43-year-old man with primary lung cancer of the right upper lobe was referred to our hospital. Initial blood tests revealed a markedly elevated serum CEA level of 1160.0 ng/mL. Chest CT identified a 55-mm tumor in the right hilar region, with enlargement of the right hilar and prevascular (#3a) lymph nodes (c-T3N2M0, Stage IIIB according to the Union for International Cancer Control tumor-node-metastasis classification, 8th edition). The patient underwent a type A extended sleeve lobectomy and pulmonary vein transposition. However, due to suspected pulmonary venous return failure, a right completion pneumonectomy was performed on POD 7. The patient's serum CEA levels returned to the normal range within 2 months postoperatively. He has remained recurrence-free for more than 4 years since the surgery.
conclusionsThis case highlights that upfront surgery may be a valid treatment option in selected patients with c-Stage IIIA or IIIB disease, even in the presence of an abnormally high preoperative serum CEA level.
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