Evidence map›Paper›PMID 42421954›Full record

ReviewFrontiers in immunology2026

CD169-positive macrophages in lymph nodes and the tumor microenvironment: harnessing their biology for clinical diagnosis and anticancer therapeutic strategies.

Ryo Fukuda, Yukio Fujiwara, Toru Maruyama, Yoshihiro Komohara

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ryo FukudaDepartment of Cell Pathology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Chuo-ku, Kumamoto, Japan.
Yukio FujiwaraDepartment of Cell Pathology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Chuo-ku, Kumamoto, Japan.
Toru MaruyamaDepartment of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Chuo-ku, Kumamoto, Japan.
Yoshihiro KomoharaDepartment of Cell Pathology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Chuo-ku, Kumamoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD169

Indexed as

Lymph NodesMacrophagesNeoplasmsSialic Acid Binding Ig-like Lectin 1Tumor-Associated MacrophagesTumor MicroenvironmentAnimalsBiomarkers, TumorHumansImmunotherapyBiomarkers, TumorSialic Acid Binding Ig-like Lectin 1SIGLEC1 protein, humancancer immunologycancer immunotherapyCD169diagnostic biomarkerlymph nodemacrophagetumor microenvironment

Identifiers

PMID42421954
PMCPMC13341932

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.