ArticleFrontiers in nutrition2026
NRS2002-stratified body composition and laboratory characteristics in hospitalized cancer patients assessed by bioelectrical impedance analysis.
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: The body composition and laboratory characteristics underlying Nutritional Risk Screening 2002 (NRS2002)-defined nutritional risk in hospitalized patients with cancer remain insufficiently described. Methods: This single-center retrospective cross-sectional study included 998 hospitalized patients with cancer. Nutritional risk was defined as NRS2002 ≥3. Bioelectrical impedance analysis (BIA) parameters and laboratory indicators related to inflammation and nutritional status were compared across NRS2002 categories. Multivariable logistic regression was used to assess adjusted associations between key body composition parameters and nutritional risk after adjustment for age, sex, body mass index, and cancer group. Results: Across increasing NRS2002 categories, extracellular water-to-total body water ratio increased, whereas body mass index decreased. Among laboratory indicators, albumin and hemoglobin tended to decrease, whereas C-reactive protein (CRP) tended to increase. In multivariable analyses, albumin was inversely associated with nutritional risk in the model without CRP (OR = 0.958, 95% CI 0.928-0.989, Conclusion: Laboratory indicators related to inflammation and nutritional status showed more consistent associations with NRS2002-defined nutritional risk than single-time-point BIA-derived body composition parameters. BIA-derived parameters may provide complementary information on body composition, but their interpretation should consider clinical status and the limitations of single-time-point assessment.
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