Evidence map›Paper›PMID 42421894›Full record

ArticleNeurosurgery practice2026

Autologous Fat Grafting to Prevent Erosion and Pain Over Neuromodulation Hardware: Technical Case Series.

Noah J Lubin, Jermaine Robertson, Melissa Janssen, Sima Mofakham, Christopher S Bellber, Sami U Khan, Charles B Mikell

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Article in Neurosurgery practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Noah J LubinDepartment of Neurosurgery, Renaissance School of Medicine, Stony Brook University, Stony Brook, New York, USA.ORCID https://orcid.org/0009-0002-6736-9825
Jermaine RobertsonDepartment of Neurosurgery, Renaissance School of Medicine, Stony Brook University, Stony Brook, New York, USA.
Melissa JanssenDepartment of Neurosurgery, Renaissance School of Medicine, Stony Brook University, Stony Brook, New York, USA.
Sima MofakhamDepartment of Neurosurgery, Renaissance School of Medicine, Stony Brook University, Stony Brook, New York, USA.
Christopher S BellberDepartment of Plastic and Reconstructive Surgery, Renaissance School of Medicine, Stony Brook University, Stony Brook, New York, USA.
Sami U KhanCurrent affiliation: Department of General Surgery, Stony Brook University Hospital, Stony Brook, New York, USA.
Charles B MikellDepartment of Neurosurgery, Renaissance School of Medicine, Stony Brook University, Stony Brook, New York, USA.ORCID https://orcid.org/0000-0002-0701-2325

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesImplanted neuromodulatory devices can be threatened by thin overlying tissue and refractory device-associated pain, both of which present significant clinical challenges with few reliable management strategies. We describe the technical workflow and preliminary clinical outcomes of autologous fat graft (AFG) for the management of neuromodulation device-related pain and dermal erosion.

methodsThis retrospective single-center technical case series details the indications, operative technique, and early postoperative results in 2 patients treated with a novel application of a standard plastic surgery technique in the context of functional neurosurgery. Autologous fat was harvested from patient donor sites and applied around a spinal cord stimulator to alleviate pain in one case and around a deep brain stimulation electrode to prevent dermal erosion in the other. Patients were followed for a minimum of 1 month of postoperative care.

resultsIn both cases, AFG successfully addressed the hardware-related complication without requiring complete device revision. The first patient experienced substantial and durable pain reduction for 2 years before requiring repeat grafting due to progressive graft resorption. In the second case, improved scalp thickness prevented progression of early erosion, although mild thinning was noted at 1 month. No perioperative complications occurred in either case.

conclusionThis early technical experience demonstrates that AFG is feasible, well-tolerated, and may provide meaningful symptomatic and reconstructive benefit as a minimally invasive adjunct in neuromodulation surgery. Longer-term prospective evaluation is required before definitive conclusions regarding durability and clinical efficacy can be drawn.

Indexed as

Autologous fat graftsCase seriesDeep brain stimulationFunctional neurosurgerySpinal cord stimulationTechnical note

Identifiers

PMID42421894
PMCPMC13345042

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