Evidence map›Paper›PMID 42421893›Full record

ArticleNeurosurgery practice2026

Comparison of Bilateral and Unilateral Chronic Subdural Hematomas: A Retrospective Multi-institutional Cohort Study.

Anoop S Chinthala, Trenton A Line, Barnabas Obeng-Gyasi, Gordon Mao, Jamie Bradbury, Aditya Mittal, Ryan T Kellogg, Enyinna Nwachuku, David O Okonkwo, Jan Vargas and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurosurgery practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anoop S ChinthalaDepartment of Neurological Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID https://orcid.org/0000-0002-6065-1177
Trenton A LineDepartment of Neurological Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Barnabas Obeng-GyasiDepartment of Neurological Surgery, Allegheny Health Network, Pittsburgh, Pennsylvania, USA.
Gordon MaoDepartment of Neurological Surgery, Indiana University Health, Indianapolis, Indiana, USA.
Jamie BradburyDepartment of Neurological Surgery, Indiana University Health, Indianapolis, Indiana, USA.
Aditya MittalDepartment of Neurological Surgery, University of Utah Health, Salt Lake City, Utah, USA.
Ryan T KelloggDepartment of Neurosurgery, University of Virginia, Charlottesville, Virginia, USA.
Enyinna NwachukuDepartment of Neurosurgery, Penn State Health, Hershey, Pennsylvania, USA.
David O OkonkwoDepartment of Neurosurgery, UPMC Healthcare System, Pittsburgh, Pennsylvania, USA.
Jan VargasDivision of Neurosurgery, PRISMA Health, Greenville, South Carolina, USA.
Matthew PeaseDepartment of Neurological Surgery, Indiana University Health, Indianapolis, Indiana, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesChronic subdural hematoma (cSDH) is a major public health issue in the United States. cSDH can present as unilateral or bilateral collections. We compared outcomes of surgically treated unilateral and bilateral cSDH and assessed factors contributing to retreatment.

methodsWe performed a retrospective cohort study through chart review of patients operated for cSDH from 4 level 1 trauma centers, February 2009 to August 2021. Patients were categorized into 3 groups: (1) unilateral, operated cSDH; (2) bilateral, operated cSDH on both sides; and (3) bilateral cSDH, but only one side operated. Patients with middle meningeal artery embolization were excluded. Data on demographics, clinical presentation, radiological findings, and outcomes were collected. A multivariable logistic regression model assessed factors associated with retreatment.

resultsWe analyzed a total of 731 patients: 563 (77%) had unilateral operated cSDH; 132 (18%) had bilateral operated cSDH; and 36 (5%) had bilateral cSDH but were operated only on one side. We found no significant differences in retreatment rates between patients with bilateral, operated cSDH and those with unilateral, operated cSDH (14% vs 12%,

conclusionThere was no significant difference in retreatment, 30-day readmission, or 30-day mortality between unilateral and bilateral cSDHs treated surgically. Despite exclusion of bilateral cSDH from major recent clinical trials, their rates of recurrence are similar to unilateral cSDH.

Indexed as

BilateralChronic subdural hematomaRecurrenceUnilateral

Identifiers

PMID42421893
PMCPMC13344927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.