Evidence map›Paper›PMID 42421877›Full record

ArticleFrontiers in surgery2026

Modified high-entry C1 screw placement for bilateral persistent first intersegmental artery in atlantoaxial instability: a case report.

In-Suk Bae, Hyoung-Joon Chun

Abstract readCase Reports
In one paragraph

Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

In-Suk BaeDepartment of Neurosurgery, Nowon Eulji Medical Center, Eulji University, Seoul, Republic of Korea.
Hyoung-Joon ChunDepartment of Neurosurgery, Hanyang University Medical Center, Hanyang University, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Atlantoaxial instability (AAI) is a recognized cervical manifestation of rheumatoid arthritis (RA) and may require posterior C1-C2 fixation. Conventional C1 lateral mass screw placement can be hazardous when anomalous vertebral artery (VA) anatomy is present, particularly in patients with persistent first intersegmental artery (PFIA). Case description: A 70-year-old woman with long-standing RA presented with a 6-month history of nuchal pain, rotational neck pain, and occipital neuralgia. Plain radiographs demonstrated AAI with an atlantodental interval of 7.5 mm, and magnetic resonance imaging revealed widening of the C1-C2 interspinous space without spinal cord compression. Computed tomography (CT) angiography revealed bilateral PFIA, with both VAs ascending directly into the foramen magnum without traversing the transverse foramen of C1. Because this anatomy directly intersected the conventional C1 lateral mass screw trajectory, a modified high-entry point was selected at the junction of the posterior arch and lateral mass. C1 lateral mass-C2 pedicle screw fixation was performed without intraoperative vascular or neural complication, and postoperative CT confirmed satisfactory implant placement. Early postoperative neck pain and occipital neuralgia improved. Conclusion: In patients with RA-associated AAI and bilateral PFIA, the standard C1 lateral mass trajectory may be unsafe. This case illustrates that a modified high-entry C1 screw placement can be a feasible alternative when guided by careful preoperative vascular imaging and individualized surgical planning.

Indexed as

atlantoaxial instabilityC1 screwpersistent first intersegmental arteryrheumatoid arhritisvertebral artery

Identifiers

PMID42421877
PMCPMC13341667

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