Evidence map›Paper›PMID 42421655›Full record

ArticleChirality2026

A Convenient Strategy to Access Diverse Libraries of Amphiphilic Compounds Based on Glycopeptoids.

Ludovica Dei, Stefano Cadeddu, Claude Taillefumier, Chiara Migone, Angela Fabiano, Anna Maria Piras, Maria Chiara Santangelo, Sebastiano Di Pietro, Valeria Di Bussolo, Gaetano Angelici

Abstract read
In one paragraph

Article in Chirality, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ludovica DeiDipartimento di Chimica e Chimica Industriale, Università di Pisa, Pisa, Italy.
Stefano CadedduDipartimento di Chimica e Chimica Industriale, Università di Pisa, Pisa, Italy.
Claude TaillefumierUniversité Clermont Auvergne, Clermont Auvergne INP, CNRS, ICCF, Clermont-Ferrand, France.
Chiara MigoneDipartimento di Farmacia, Università di Pisa, Pisa, Italy.
Angela FabianoDipartimento di Farmacia, Università di Pisa, Pisa, Italy.ORCID https://orcid.org/0000-0003-3912-840X
Anna Maria PirasDipartimento di Farmacia, Università di Pisa, Pisa, Italy.
Maria Chiara SantangeloDipartimento di Farmacia, Università di Pisa, Pisa, Italy.
Sebastiano Di PietroDipartimento di Farmacia, Università di Pisa, Pisa, Italy.
Valeria Di BussoloDipartimento di Farmacia, Università di Pisa, Pisa, Italy.
Gaetano AngeliciDipartimento di Chimica e Chimica Industriale, Università di Pisa, Pisa, Italy.

Funding

H2020 Marie Skłodowska-Curie Actions 656157-Pro-Membrane-H2020-MSCA-IF-2014PNRR project "Tuscany Health Ecosystem (THE)" CUP I53C22000780001PNRR project "Tuscany Health Ecosystem (THE)" ECS00000017
6 · The paper itself

Abstract

A convergent synthetic approach has been developed to access a potentially wide library of amphiphilic glycopeptoids. The intrinsic modularity of apolar peptoid units, coupled with the ability to conjugate various two-headed monosaccharide units, enables the exploration of a vast chemical space for the precise regulation of amphiphilic properties and the formation of diverse nanomaterials through self-assembly. A full characterization of the physical and chemical properties of the self-assembled materials obtained has been conducted on some representative molecular structures designed for the formation of aggregates. The comprehension of the relation between the molecular structure of this family of amphiphilic compounds and their self-assembly could lead to the "on demand synthesis" of functional excipient for drug delivery or compounds for the stabilization and crystallization of membrane proteins.

Indexed as

PeptoidsSurface-Active AgentsMicellesStereoisomerismMicellesPeptoidsSurface-Active Agentsamphiphilic moleculesglycopeptoidsmicellespeptoidsself‐assembly

Identifiers

PMID42421655
PMCPMC13347205

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.