Evidence map›Paper›PMID 42421571›Full record

ArticleInfluenza and other respiratory viruses2026

Correlations and Timeliness of Respiratory Syncytial Virus Surveillance Indicators-United States, 2018-2024.

Erin L Anderson, Erica Billig Rose, Amber Winn, Sophia Chkonia, Heidi Moline, Ariana Toepfer, Monica E Patton, Christopher A Taylor, Aaron Kite-Powell, Stephanie Dietz and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Influenza and other respiratory viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Erin L AndersonCoronavirus and Other Respiratory Viruses Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID https://orcid.org/0009-0006-1364-0025
Erica Billig RoseCoronavirus and Other Respiratory Viruses Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0001-7056-511X
Amber WinnCoronavirus and Other Respiratory Viruses Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Sophia ChkoniaCoronavirus and Other Respiratory Viruses Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0002-0570-8628
Heidi MolineCoronavirus and Other Respiratory Viruses Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Ariana ToepferCoronavirus and Other Respiratory Viruses Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Monica E PattonCoronavirus and Other Respiratory Viruses Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Christopher A TaylorCoronavirus and Other Respiratory Viruses Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0002-0937-5461
Aaron Kite-PowellOffice of Public Health Data, Surveillance, and Technology, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Stephanie DietzOffice of Public Health Data, Surveillance, and Technology, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Michael SheppardOffice of Public Health Data, Surveillance, and Technology, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Jourdan DeViesOffice of Public Health Data, Surveillance, and Technology, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Benjamin J SilkCoronavirus and Other Respiratory Viruses Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRespiratory syncytial virus (RSV) is a major cause of hospitalizations in young children and older adults in the United States. Monitoring seasonal RSV activity through national surveillance systems and understanding the relationships among RSV surveillance indicators can help ensure timely administration of prevention products and improve preparedness among healthcare systems and public health programs.

methodsWe analyzed RSV data across six surveillance years from the National Respiratory and Enteric Virus Surveillance System (NREVSS), National Syndromic Surveillance Program (NSSP), commercial laboratories, New Vaccine Surveillance Network (NVSN), and Respiratory Syncytial Virus Hospitalization Surveillance Network (RSV-NET). We characterized RSV seasonality and compared pediatric and all-age surveillance indicators (percent positivity, percentage of ED visits, and hospitalization rates) at key points during the RSV season. We then estimated cross-correlations and lags between each system and NREVSS before, during, and after the COVID-19 pandemic.

resultsFive RSV seasons occurred between 2018 and 2024. Pediatric indicators were greater than all-age indicators at NREVSS season onset (range: 1.4-6.3 times greater), peak (1.3-5.8), and offset (1.1-4.7). Nationally, indicators were highly correlated across systems (ρ > 0.92) during the prepandemic and postdisruption periods, with minimal lags (0-1 weeks). However, correlations (ρ = 0.48-0.99) and lags (0-6 weeks) varied across regions and time windows during these periods.

conclusionsPediatric surveillance indicators provide the earliest indications of RSV season onset. CDC systems that provide complementary data on RSV activity and associated outcomes are highly correlated at the national and regional levels but may not capture local trends that are important for optimizing prevention.

Indexed as

Epidemiological MonitoringRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsAdolescentChildChild, PreschoolHospitalizationHumansInfantPopulation SurveillanceSeasonsUnited Statescorrelationpediatricsrespiratory syncytial virusseasonalitysurveillance

Identifiers

PMID42421571
PMCPMC13347139

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.