ArticleJournal of clinical neurology (Seoul, Korea)2026
Role of Physical Activity in Protecting Against Dementia According to Menopausal Status.
Article in Journal of clinical neurology (Seoul, Korea), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
background and purposeThis study evaluated the impact of physical activity on dementia risk in females while considering their menopausal status and body mass index (BMI) as potential modifiers.
methodsThis population-based retrospective cohort study utilized the Korean National Health Insurance Service database, and stratified 2,163,842 females aged ≥40 years who underwent health examinations in 2009 into pre- and postmenopausal groups. Cox proportional-hazards models were used to estimate the adjusted hazard ratios (aHRs) for all-cause dementia, Alzheimer's dementia (AD), and vascular dementia (VaD) according to physical activity levels. Interaction terms were used to assess effect modification by BMI.
resultsRegular physical activity was associated with a reduced risk of all-cause dementia and AD, but not VaD in premenopausal females (aHR=0.830, 95% confidence interval [CI]=0.739-0.931) and a reduced risk of all-cause dementia, AD, and VaD in postmenopausal females (e.g., aHR=0.884, 95% CI=0.868-0.900). The association between physical activity and dementia risk was largely consistent across BMI categories. However, a modest interaction was observed for light physical activity (LPA) (
conclusionsPhysical activity is associated with a lower risk of dementia in both pre- and postmenopausal females. Among postmenopausal females, even LPA such as walking may confer protective benefits, particularly in those with higher BMIs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.