ArticleSe pu = Chinese journal of chromatography2026
[Simultaneous determination of five common pyrethroid metabolites in urine using liquid-liquid extraction coupled with ultra performance liquid chromatography-tandem mass spectrometry].
Article in Se pu = Chinese journal of chromatography, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Pyrethroids are extensively employed in agricultural pest management and household sanitation practices. However, their widespread use has raised concerns as they pose a multitude of health risks to humans. Consequently, the development of precise, highly sensitive, and efficient biomonitoring techniques for evaluating internal exposure levels of pyrethroids across different populations has emerged as a paramount goal in the field of environmental exposure and health effect research. This study developed a method using ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) for the simultaneous determination of five common pyrethroid metabolites in urine, with sample pretreatment involving hydrochloric acid hydrolysis and liquid-liquid extraction. The method was optimized for mass spectrometric acquisition parameters and liquid chromatography separation conditions. Chromatographic separation was successfully accomplished utilizing a BEH C
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