Evidence map›Paper›PMID 42421108›Full record

ArticleBorderline personality disorder and emotion dysregulation2026

A pilot randomized controlled trial of mentalization-based treatment and structured clinical management for outpatients with borderline personality disorder in South Korea.

HyunKyung Shin, Wonjun Choi, You Sun Chung, Haein Park, Uk-Jin Oh, Sun-Woo Choi, Ju-Yeal Lee, Seokho Yun, Bokyung Choo, Bon-Hoon Koo and 1 more

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Article in Borderline personality disorder and emotion dysregulation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

HyunKyung ShinInstitute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Wonjun ChoiInstitute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
You Sun ChungInstitute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Haein ParkDepartment of Psychiatry, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Republic of Korea.
Uk-Jin OhDepartment of Psychiatry, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Sun-Woo ChoiSamsung SDI Open Counseling Center, Yongin, Republic of Korea.
Ju-Yeal LeeWalking Together Psychological Counseling Center, Seoul, Republic of Korea.
Seokho YunDepartment of Psychiatry, Yeungnam University Hospital, Yeungnam University College of Medicine, Daegu, Republic of Korea.
Bokyung ChooInstitute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Bon-Hoon KooDepartment of Psychiatry, Yeungnam University Hospital, Yeungnam University College of Medicine, Daegu, Republic of Korea.
Jeong-Ho SeokInstitute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea. johnstein@yuhs.ac.ORCID https://orcid.org/0000-0002-9402-7591

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the effectiveness of mentalization-based treatment (MBT) for borderline personality disorder (BPD) compared to structured clinical management (SCM) in a South Korean clinical setting.

methodsThis single-blind pilot randomized controlled trial included 64 individuals with a primary diagnosis of BPD who underwent either MBT (n = 37) or SCM (n = 27) in an outpatient setting over 12 months. Both interventions included weekly individual and group sessions. The primary outcome measure was the number of suicide attempts. Secondary outcomes included depressive symptoms, suicide risk, hospitalization frequency and duration, mentalization difficulties, adult attachment styles, BPD symptom severity, and resilience. Outcomes were assessed at baseline and 6 and 12 months. Analyses were conducted using generalized estimating equations, following the intention-to-treat principle.

resultsBoth treatment groups demonstrated a significant reduction in suicide attempts over 12 months, with no significant between-group differences in the primary outcome. However, participants receiving MBT showed consistent and sustained improvements in depressive symptoms, mentalization difficulties, and resilience. MBT was also associated with a significant reduction in attachment anxiety at 12 months, whereas the SCM produced earlier reductions in suicide risk and improvements in psychic equivalence. No significant changes were observed in attachment avoidance or in the hasty and incomplete mentalizing domains in either group.

conclusionsThis pilot trial provides preliminary evidence that both MBT and SCM were effective in reducing suicidal behaviors and enhancing psychological functioning among Koreans with BPD. MBT demonstrated greater long-term benefits in emotion regulation and adaptability, suggesting that it may serve as a culturally scalable intervention in non-Western clinical settings.

Indexed as

Borderline personality disorderMentalization-based treatmentRandomized controlled trialStructured clinical management

Identifiers

PMID42421108
PMCPMC13628851

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.