Evidence map›Paper›PMID 42421064›Full record

ArticleBMC medicine2026

Comparing geriatric assessment tools for predicting negative health outcomes in older adults.

Ahmad Abbadi, Francesco Innocenti, Giorgi Beridze, Emmanouil Kokoroskos, Alberto Zucchelli, Tobias Nordström, Caroline Wachtler, Laura Fratiglioni, Davide L Vetrano, Amaia Calderón-Larrañaga

Abstract readComparative Study
In one paragraph

Article in BMC medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ahmad Abbadi *Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Solna, Sweden. ahmad.abbadi@ki.se.ORCID 0000-0001-9373-668X
Francesco Innocenti *Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Solna, Sweden.ORCID 0000-0002-3717-267X
Giorgi BeridzeAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Solna, Sweden.ORCID 0000-0002-2615-226X
Emmanouil KokoroskosAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Solna, Sweden.ORCID 0009-0007-4250-2294
Alberto ZucchelliAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Solna, Sweden.ORCID 0000-0001-5992-8506
Tobias NordströmDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden.ORCID 0000-0003-4915-7546
Caroline WachtlerUnit for Analysis, Public Health Agency of Sweden, Stockholm, Sweden.ORCID 0000-0002-1317-7732
Laura FratiglioniAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Solna, Sweden.ORCID 0000-0002-6374-6614
Davide L VetranoAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Solna, Sweden.ORCID 0000-0002-3099-4830
Amaia Calderón-LarrañagaAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Solna, Sweden.ORCID 0000-0001-9064-9222

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAmid global population aging, evidence-based geriatric assessment tools are essential for clinical decision-making and risk stratification. Despite growing interest, few studies have comprehensively compared the discriminative ability of existing tools, particularly as new tools have recently become available. In this study, we aimed to perform such a comparison across a wide range of patient-relevant health outcomes.

methodsThis population-based prospective cohort study used data from the Swedish National study on Aging and Care in Kungsholmen (SNAC-K). We included 3,108 adults aged ≥ 60 years at baseline (2001-2004), who were followed up for up to six years. Seven tools (Health Assessment Tool [HAT], SNAC-K Frailty Index (FI) [SNACK-FI], Primary Care FI [PC-FI], Intrinsic Capacity [IC], Geriatric 8 [G8], Charlson Comorbidity Index [CCI], and Cumulative Illness Rating Scale [CIRS]) were evaluated in terms of their discriminative ability for formal care use, institutionalization, dementia, disability, injurious falls, self-rated health, quality of life, unplanned hospitalization, and mortality, using Harrell's C-index estimated from unadjusted cause-specific Cox models.

resultsHAT, IC, and SNACK-FI consistently ranked among the top three performers across all outcomes. The highest C-indices were observed for institutionalization (HAT 0.93 [0.91, 0.95], IC 0.93 [0.90, 0.94], SNACK-FI 0.92 [0.89, 0.94]); 1-year mortality (HAT 0.88 [0.85, 0.91], SNACK-FI 0.87 [0.84, 0.91], IC 0.86 [0.82, 0.89]); dementia (HAT 0.87 [0.85, 0.89], IC 0.88 [0.86, 0.90], SNACK-FI 0.86 [0.83, 0.88]); and formal care use (HAT 0.83 [0.81, 0.86], IC 0.85 [0.83, 0.88], SNACK-FI 0.80 [0.77, 0.83]). Tools incorporating physical function metrics (e.g., gait speed) showed higher discriminative ability than those that omitted them. IC and SNACK-FI showed marginal and clinically negligible occasional gains over HAT ( ≤ 0.02 differences in C-index), despite greater complexity and a larger number of indicators. Guideline-endorsed tools (e.g., G8, CCI, CIRS) showed comparatively lower discrimination across outcomes.

conclusionsContemporary geriatric assessment tools show promise. Tools incorporating physical function metrics demonstrated superior discriminative ability, suggesting these measures may be integral to geriatric prognosis and risk stratification. Given the underperformance of several established tools, reappraisal of current guideline recommendations may be warranted.

Indexed as

Geriatric AssessmentAgedAged, 80 and overFemaleHumansMaleMiddle AgedProspective StudiesQuality of LifeSwedenClinical decision-makingGeriatric assessmentGeriatric health careProspective cohort studyRisk adjustment

Identifiers

PMID42421064
PMCPMC13348859

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.