Evidence map›Paper›PMID 42420692›Full record

ArticleJournal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology2026

Development and validation of a deep learning model for radiographic classification of pediatric femoral neck fractures.

WenTao Wang, ShengHua He, LiHong Ou, Federico Canavese, Antonio Andreacchio, Chiara Arrigoni, Nunzio Catena, Marco Corradin, Mariabeatrice Damasio, Valentina Camurri and 36 more

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Article in Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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46 authors.

WenTao Wang *The fourth Clinical Medical College of Guangzhou University of Chinese Medicine, ShenZhen, GuangDong, China. wangwt53@mail2.sysu.edu.cn.ORCID http://orcid.org/0000-0001-7506-6651
ShengHua He *The fourth Clinical Medical College of Guangzhou University of Chinese Medicine, ShenZhen, GuangDong, China.
LiHong Ou *School of Integrated Circuits (International School of Microelectronics), Dongguan University of Technology, 1st DaXue Road, SongShanHu District, DongGuan, 523808, GuangDong, China.
Federico CanaveseOrthopedic and Traumatology Department, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genoa, Italy.
Antonio AndreacchioDepartment of Pediatric Orthopedics, Vittore Buzzi Children's Hospital, Milan, Italy.
Chiara ArrigoniHand and Microsurgery Unit, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genoa, Italy.
Nunzio CatenaHand and Microsurgery Unit, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genoa, Italy.
Marco CorradinOrthopedic and Traumatology Department, Alto Vicentino Hospital, Via Garziere 42, Santorso, Italy.
Mariabeatrice DamasioDepartment of Radiology, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genoa, Italy.
Valentina CamurriOrthopedic and Traumatology Department, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genoa, Italy.
Francesco CandussoOrthopedic and Traumatology Department, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genoa, Italy.
Claudia De CristoDepartment of General Surgery and Medical Surgical Specialties, Section of Orthopaedics and Trarumatology, Policlinico Rodolico-San Marco, University of Catania, Catania, Italy.
Camilla De LucaDepartment of Radiology, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genoa, Italy.
Sara De SalvoOrthopedic and Traumatology Department, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genoa, Italy.
Cristina Di GrigoliDepartment of Pediatric Orthopedics, Vittore Buzzi Children's Hospital, Milan, Italy.
Roberto FacchiOrthopedic and Traumatology Department, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genoa, Italy.
Andrea FlorianOrthopedic and Traumatology Department, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genoa, Italy.
Cesare GalloOrthopedic and Traumatology Department, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genoa, Italy.
Claudio GargiuloOrthopedic and Traumatology Department, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genoa, Italy.
Rocco GrilloDepartment of Radiology, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genoa, Italy.
Laura GiarratanaDepartment of Pediatric Orthopedics, Vittore Buzzi Children's Hospital, Milan, Italy.
Emanuela LanariOrthopedic and Traumatology Department, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genoa, Italy.
Veronica LodoviciOrthopedic and Traumatology Department, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genoa, Italy.
Giovanni LucchesiDeaprtment of Pediatric Orthopaedics, Orthochildren Center, Bologna, Italy.
Ludovico LucentiDepartment of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy.
Francesca MagnaguagnoDepartment of Radiology, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genoa, Italy.
Lorenza MarengoOrthopedic and Traumatology Department, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genoa, Italy.
Vittoria MazzolaOrthopedic and Traumatology Department, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genoa, Italy.
Angelo MussoOrthopedic and Traumatology Department, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genoa, Italy.
Luigi Aurelio NastoDepartment of Orthopedics, Azienda Ospedaliera Universitaria "Luigi Vanvitelli", University of Campania "Luigi Vanvitelli" School of Medicine, Naples, Italy.
Vito PavoneDepartment of General Surgery and Medical Surgical Specialties, Section of Orthopaedics and Trarumatology, Policlinico Rodolico-San Marco, University of Catania, Catania, Italy.
Andrea PellegrinoOrthopedic and Traumatology Department, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genoa, Italy.
Marco RamellaDepartment of Pediatric Orthopedics, Vittore Buzzi Children's Hospital, Milan, Italy.
Francesca RizzoDepartment of Radiology, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genoa, Italy.
Marco SapienzaDepartment of General Surgery and Medical Surgical Specialties, Section of Orthopaedics and Trarumatology, Policlinico Rodolico-San Marco, University of Catania, Catania, Italy.
Nicola StagnaroDepartment of Radiology, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genoa, Italy.
Gianluca TestaDepartment of General Surgery and Medical Surgical Specialties, Section of Orthopaedics and Trarumatology, Policlinico Rodolico-San Marco, University of Catania, Catania, Italy.
Andrea VescioDepartment of Life Science, Health and Health Professions, Link Campus University, Rome, Italy.
XiaoLiang ChenDepartment of Orthopedics, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.
ChongZhi ZhaoDepartment of Pediatric Orthopedics, Foshan Hospital of Traditional Chinese Medicine, FoShan, GuangDong, China.
DongKe LaiDepartment of Orthopedics, Mindong Hospital of Ningde City, NingDe, FuJian, China.
Hang LiuDepartment of Pediatric Orthopedics, Children's Hospital of Chongqing Medical University, ChongQing, China.
ChunXing WuDepartment of Pediatric Orthopedics, Children's Hospital of Fudan University, National Children's Medical Center, ShangHai, China.
ShunYou ChenDepartment of Pediatric Orthopedics, Fuzhou Second General Hospital, 47th ShangTeng Road, CangShan District, FuZhou, 350007, FuJian, China. csy508@163.com.
SuiGu TangSchool of Integrated Circuits (International School of Microelectronics), Dongguan University of Technology, 1st DaXue Road, SongShanHu District, DongGuan, 523808, GuangDong, China. tangsuigu@dgut.edu.cn.
QianQian MeiDepartment of Pediatric Orthopedics, Shenzhen Children's Hospital, 7019th YiTian Road, FuTian District, ShenZhen, 518026, GuangDong, China. QianqianMei2023@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Delbet-Colonna (DC) classification guides treatment of pediatric femoral neck fractures (PFNFs) but relies on clinical experience. No deep learning (DL) model has been developed and validated to differentiate between PFNFs and proximal femoral growth plates (PFGPs) and classify PFNFs via DC classification, in order to overcome this limitation. MATERIALS AND

methodsX-ray data including the annotations of 5555 PFGPs, 1306 PFNFs with various DC types, and 257 pediatric subtrochanteric femoral fractures (PSFFs), were prepared to construct a DL model based on the you-only-look-once (YOLO) model with wavelet transform (WT) and attention mechanism (AM) architectures. Two senior-level pediatric orthopedic surgeons (POS) performed the annotations independently by referring to the postoperative X-rays. The annotations were finalized if there were no differences. Otherwise, the two POS discussed and determined the final annotation. Thirty-one POS with different experience assessed the external testing dataset twice, without (first) and with (second) YOLO-WTAM model assistance. The rating performances of the YOLO-WTAM model and POS were evaluated. The kappa value reflecting reliability was obtained using a Fleiss kappa analysis.

resultsAccording to the internal testing dataset, the area under the curve for different annotations ranged from 0.94 to 0.99. According to the external testing dataset, in the second round, the accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were greater than those in the first (P < 0.001): 79.17-87.16%, 83.30-87.47%, 94.68-96.57%, 74.62-79.44%, and 92.97-95.55%, respectively. Senior-level POS exhibited superior accuracy (P = 0.021), sensitivity (P = 0.013), specificity (P = 0.039), PPV (P = 0.004), and NPV (P = 0.025) in the first round but not in the second. The kappa value improved among residents (+27.36%), junior-level (+17.03%), mid-level (+26.66%), and senior-level (+17.07%) POS.

conclusionsThe YOLO-WTAM model can accurately differentiate between PFNFs and PFGPs and classify different DC types of PFNFs. This improves POSs' rating performance and reduces the need for experience in classifying PFNFs. LEVEL OF EVIDENCE: Level III.

Indexed as

Deep LearningFemoral Neck FracturesChildClassification AlgorithmsHumansRadiographyChildrenDeep learningDelbet–ColonnaDetectionFemoral neck fracture

Identifiers

PMID42420692
PMCPMC13654910

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