Evidence map›Paper›PMID 42420549›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2026

Association between reticulocyte hemoglobin content (RetHe) and neurodevelopmental outcomes in preterm infants.

Grace K Mueller, Miheret Yitayew, Amanda Robinson, Roy Sabo, Karen D Hendricks-Muñoz

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Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Grace K MuellerChildren's Hospital of Richmond at Virginia Commonwealth University Health System, Richmond, VA, USA. grace.mueller@pediatrix.com.ORCID http://orcid.org/0000-0001-7384-3269
Miheret YitayewChildren's Hospital of Richmond at Virginia Commonwealth University Health System, Richmond, VA, USA.
Amanda RobinsonC. Kenneth and Dianne Wright Center for Clinical and Translational Research, Virginia Commonwealth University, Richmond, VA, USA.
Roy SaboC. Kenneth and Dianne Wright Center for Clinical and Translational Research, Virginia Commonwealth University, Richmond, VA, USA.
Karen D Hendricks-MuñozChildren's Hospital of Richmond at Virginia Commonwealth University Health System, Richmond, VA, USA.ORCID http://orcid.org/0000-0002-6367-0373

Funding

Gerber Foundation 11193
6 · The paper itself

Abstract

objectiveInvestigate the impact of reticulocyte hemoglobin content (RetHe) on neurodevelopment in preterm infants. STUDY

designRetrospective cohort of infants born ≤36

results52% of 381 infants (N = 199) had at least 1 low RetHe. Infants with abnormal development had lower average and minimum RetHe, and longer exposure to low RetHe (all p ≤ 0.003). RetHe was highest in infants born 32-33 weeks GA. Higher RetHe during postnatal weeks 1-5 was associated with higher Test of Infant Motor Performance Z-scores (p = 0.0048), with diminishing effect over time, but decreasing 12-month Bayley cognitive Z-scores (p = 0.0064).

conclusionRetHe is associated with neurodevelopment and potentially has differential effects based on GA and postnatal age.

Identifiers

PMID42420549

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.