Evidence map›Paper›PMID 42420542›Full record

ArticleNature medicine2026

Global breast cancer survival estimates in 2017-2021 to advance the WHO Global Breast Cancer Initiative.

Fabio Girardi, Mary Nyangasi, Charlton Callender, Marie Ng, Saki Narita, Julie Torode, Heba AlSawahli, Sok King Ong, Freddy Gnangnon, Valerie McCormack and 5 more

Abstract read
In one paragraph

Article in Nature medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Fabio Girardi *Division of Medical Oncology 2, Veneto Institute of Oncology IRCCS, Padua, Italy. girardif@who.int.ORCID http://orcid.org/0000-0001-7094-7986
Mary Nyangasi *Department of Noncommunicable Diseases and Mental Health, World Health Organization, Geneva, Switzerland.
Charlton CallenderDepartment of Data, Digital Health, Analytics and Artificial Intelligence, World Health Organization, Geneva, Switzerland.ORCID http://orcid.org/0000-0002-4367-3649
Marie NgYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Saki NaritaDepartment of Data, Digital Health, Analytics and Artificial Intelligence, World Health Organization, Geneva, Switzerland.ORCID http://orcid.org/0000-0002-7214-8851
Julie TorodeInstitute of Cancer Policy, King's College, London, UK.
Heba AlSawahliDepartment of Health Promotion, Disease Prevention and Control, World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt.
Sok King OngEnvironmental Health Services, Ministry of Health, Bandar Seri Begawan, Brunei Darussalam.ORCID http://orcid.org/0000-0001-8176-8561
Freddy GnangnonDivision of Surgical Oncology, Faculty of Health Sciences, University of Abomey-Calavi, Cotonou, Benin.
Valerie McCormackEnvironment and Lifestyle Epidemiology Branch, International Agency for Research on Cancer, Lyon, France.ORCID http://orcid.org/0000-0001-7397-3442
Wael ShelpaiMinistry of Health and Prevention, National Cancer Registry, Dubai, United Arab Emirates.
RizuDepartment of Noncommunicable Diseases and Mental Health, World Health Organization, Geneva, Switzerland.
Lamia MahmoudDepartment of Health Promotion, Disease Prevention and Control, World Health Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt.
Haidong WangDepartment of Data, Digital Health, Analytics and Artificial Intelligence, World Health Organization, Geneva, Switzerland.
André M IlbawiDepartment of Noncommunicable Diseases and Mental Health, World Health Organization, Geneva, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The World Health Organization (WHO) Global Breast Cancer Initiative aims to attain meaningful global breast cancer mortality reductions by 2040-a target that hinges on improvements in patient outcomes and survival. So far, however, data on cancer survival remain limited in low- and middle-income countries. The WHO estimated population-based age-standardized 5-year net survival for women diagnosed with breast cancer between 2017 and 2021 across all 194 Member States, providing a global benchmark for monitoring breast cancer outcomes. Here we found that median 5-year net survival varied widely across WHO regions during 2017-2021: 39.1% (95% uncertainty interval 34.1-44.7%) in the African Region, 61.0% (51.4-69.8%) in the Eastern Mediterranean Region, 66.3% (57.7-73.7%) in the South-East Asia Region, 81.1% (78.6-83.5%) in the Western Pacific Region, 84.0% (82.8-85.1%) in the European Region and 88.5% (86.7-90.1%) in the Region of the Americas. Persisting disparities in survival reflect profound global inequities; sustained initiatives to narrow gaps in access to diagnosis and treatment for breast cancer are crucial to strengthening health systems. This will enable all countries to ensure optimal outcomes for their patients with breast cancer and achieve Global Breast Cancer Initiative and Sustainable Development Goals targets.

Indexed as

Breast NeoplasmsGlobal HealthFemaleHumansWorld Health Organization

Identifiers

PMID42420542
PMCPMC13577899

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.