Evidence map›Paper›PMID 42420460›Full record

ArticleNature2026

Universal cell embedding provides a foundation model for cell biology.

Yanay Rosen, Yusuf Roohani, Ayush Agrawal, Leon Samotorčan, Tabula Sapiens Consortium, Stephen R Quake, Jure Leskovec

Abstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Virtual Cells Need Context, Not Just Scale.bioRxiv : the preprint server for biology · 2026
    Article
  20. Stack: In-Context Learning of Single-Cell Biology.bioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yanay Rosen *Department of Computer Science, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-1129-9645
Yusuf Roohani *Department of Biomedical Data Science, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-9577-5014
Ayush AgrawalDepartment of Computer Science, Stanford University, Stanford, CA, USA.
Leon SamotorčanDepartment of Computer Science, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0009-0000-0292-9591
Tabula Sapiens Consortium
Stephen R QuakeBiohub, San Francisco, CA, USA. quake@stanford.edu.ORCID http://orcid.org/0000-0002-1613-0809
Jure LeskovecDepartment of Computer Science, Stanford University, Stanford, CA, USA. jure@cs.stanford.edu.ORCID http://orcid.org/0000-0002-5411-923X

Funding

Human Brain Single-Cell Genomics ExplorerU24NS146314 · NINDS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI HAUSSLER, DAVID H, ZHU, JINGCHUN · 2025 to 2025
$3.7M
NINDS NIH HHS U24 NS146314
6 · The paper itself

Abstract

Developing a universal representation space for cells that encompasses the tremendous molecular diversity of cell types across species would be transformative for cell biology. Recent work using single-cell transcriptomic approaches to create molecular definitions of cell types in the form of cell atlases has provided the necessary data for such an endeavour

Indexed as

Cell BiologyCellsModels, BiologicalAnimalsCell LineageHumansOrgan SpecificitySingle-Cell Analysis

Identifiers

PMID42420460
PMCPMC13441871

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.