Evidence map›Paper›PMID 42420253›Full record

SynthesisNutrition & diabetes2026

Beneficial effects of Chlorella species supplementation in the general population: a GRADE-assessed systematic review and dose-response meta-analysis.

Helia Mardani, Mohammad Amin Karimi, Mohammad Sharifi, Dorsa Ghazvineh, Zahra Yari, Ali Jafari

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Nutrition & diabetes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Helia MardaniStudents' Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Amin KarimiSchool of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mohammad SharifiDepartment of Nutrition, Food Sciences and Clinical Biochemistry, School of Medicine, Social Determinants of Health Research Center, Gonabad University of Medical Science, Gonabad, Iran.
Dorsa GhazvinehNon-Communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran.
Zahra YariDepartment of Nutrition Research, National Nutrition and Food Technology Research Institute and Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran. zahrayari_nut@yahoo.com.ORCID http://orcid.org/0000-0003-2796-2413
Ali JafariStudent Research Committee, Department of Community Nutrition, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Ajafari.nut@gmail.com.ORCID http://orcid.org/0000-0001-7343-027X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This systematic review and meta-analysis aimed to evaluate the potential benefits of Chlorella supplementation in the general population, with a focus on its impact across a broad spectrum of health-related biomarkers and clinical parameters. A comprehensive literature search was conducted in PubMed, CENTRAL, Web of Science, Scopus, and EMBASE databases was conducted up to February 20, 2025. A total of 24 studies were included. Chlorella supplementation led to significant reductions in body fat percentage (Weighted Mean Difference [WMD] = -0.73%, 95% Confidence Interval [CI]: -1.18 to -0.29), body mass index (BMI) (WMD = -0.30 kg/m

Indexed as

ChlorellaDietary SupplementsBiomarkersBody Mass IndexC-Reactive ProteinHumansInsulin ResistanceLeptinBiomarkersC-Reactive ProteinLeptin

Identifiers

PMID42420253
PMCPMC13631250

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.