Evidence map›Paper›PMID 42419257›Full record

ArticleEmerging microbes & infections2026

Characterization of oseltamivir-resistant A(H5N1) clade 2.3.4.4b, genotype D1.1 variants identified in poultry farms of British Columbia, Canada.

Maxime Cochin, Yacine Abed, Robert Vendramelli, Katrina Dionne, Catherine Bourassa, Geneviève Laroche, Rose Chan, Thang Truong, Anthony Signore, Yohannes Berhane and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Emerging microbes & infections, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Maxime CochinFaculty of Medecine, Université Laval, Québec, Canada.
Yacine AbedResearch Center in Infectious Diseases, CHU de Québec Research Center-Université Laval, Québec, Canada.
Robert VendramelliNational Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
Katrina DionneDépartement de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Québec, Canada.
Catherine BourassaCentre de Recherche du CHUM, Université de Montréal, Québec, Canada.
Geneviève LarocheDepartment of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Canada.
Rose ChanNational Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
Thang TruongNational Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
Anthony SignoreNational Center for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, Canada.
Yohannes BerhaneNational Center for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, Canada.
Marceline CôtéDepartment of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Canada.
Andres FinziDépartement de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Québec, Canada.
Darwyn KobasaNational Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
Guy BoivinFaculty of Medecine, Université Laval, Québec, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Highly pathogenic avian influenza A(H5N1) viruses of clade 2.3.4.4b, genotype D1.1, are responsible for widespread outbreaks in poultry and continue to cause sporadic, sometimes severe, human infections. Herein, we characterized a wild-type (WT) influenza A(H5N1) D1.1 isolate (BC-H5N1-WT) and its H275Y neuraminidase (NA) variant (BC-H5N1-H275Y), both of which emerged on farms in British Columbia, Canada, during the fall 2024 outbreak.

Indexed as

Antiviral AgentsDrug Resistance, ViralInfluenza A Virus, H5N1 SubtypeInfluenza in BirdsOseltamivirPoultry DiseasesAcids, CarbocyclicAnimalsBritish ColumbiaDibenzothiepinsDogsFarmsFemaleGenotypeHumansMadin Darby Canine Kidney CellsAcids, CarbocyclicAntiviral AgentsbaloxavirDibenzothiepinsMorpholinesNeuraminidaseOseltamivirPyridonesTriazinesViral ProteinsA(H5N1)Avian InfluenzaH5 clade 2.3.4.4bNA H275Yoseltamivir resistance

Identifiers

PMID42419257
PMCPMC13353464

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.