Evidence map›Paper›PMID 42418612›Full record

ArticleNEJM catalyst innovations in care delivery2026

Why and How to Monitor Deployed AI Systems in Health Care.

Timothy Keyes, Alison Callahan, Abby S Pandya, Nerissa Ambers, Juan M Banda, Miguel Fuentes, Carlene Lugtu, Pranav Masariya, Srikar Nallan, Connor O'Brien and 11 more

Abstract read
PubMed Publisher
In one paragraph

Article in NEJM catalyst innovations in care delivery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
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  8. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Timothy KeyesSenior Data Scientist, Stanford Health Care, Palo Alto, CA, USA.ORCID 0000-0003-0423-9679
Alison CallahanData Scientist, Stanford Health Care, Palo Alto, CA, USA.ORCID 0000-0001-5163-380X
Abby S PandyaSenior Manager, Data Science Product Management, Stanford Health Care, Stanford, CA, USA.
Nerissa AmbersDirector, Health Informatics Transformation, Stanford Health Care, Palo Alto, CA, USA.
Juan M BandaLead Data Scientist, Stanford Health Care, Stanford, CA, USA.
Miguel FuentesData Scientist, Division of Computational Medicine, Stanford University, Stanford, CA, USA.
Carlene LugtuManager, Health Informatics Transformation, Stanford Health Care, Palo Alto, CA, USA.
Pranav MasariyaLead Data Engineer, Stanford Health Care, Palo Alto, CA, USA.
Srikar NallanSenior Director, Stanford Health Care, Palo Alto, CA, USA.
Connor O'BrienData Scientist, Stanford Health Care, Palo Alto, CA, USA.
Thomas WangSenior Program Manager, Division of Computational Medicine, Stanford University, Stanford, CA, USA.
Emily AlsentzerAssistant Professor, Department of Biomedical Data Science, Stanford University, Stanford, CA, USA.
Jonathan H ChenAssociate Professor, Department of Medicine, Stanford University, Stanford, CA, USA.
Dev DashAssistant Professor, Department of Emergency Medicine, Stanford University, Stanford, CA, USA.
Matthew A EisenbergAssociate Chief Medical Information Officer, Stanford Health Care, Palo Alto, CA, USA.
Patricia GarciaAssociate Chief Medical Information Officer, Stanford Health Care, Palo Alto, CA, USA.
Nikesh KotechaSenior Director, Data Science, Stanford Health Care, Stanford, CA, USA.
Anurang RevriVice President and Chief Enterprise Architect, Stanford Health Care, Stanford, CA, USA.
Michael A PfefferChief Information and Digital Officer, Stanford Health Care, Stanford, CA, USA.
Nigam H ShahChief Data Scientist, Stanford Health Care, Stanford, CA, USA.
Sneha S JainClinical Assistant Professor, Department of Medicine, Division of Cardiovascular Medicine, Stanford University, Stanford, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postdeployment monitoring of artificial intelligence (AI) systems in health care is essential to ensure their safety, quality, and sustained benefit - and to support governance decisions about which systems to update, modify, or decommission. Motivated by these needs, the authors developed a framework for monitoring deployed AI systems organized around three complementary principles: system integrity, performance, and impact. System integrity monitoring focuses on maximizing system uptime, detecting runtime errors, and identifying when changes to the surrounding information technology ecosystem have unintended effects. Performance monitoring focuses on maintaining accurate and equitable system behavior in the face of changing health care practices (and thus input data) over time. Impact monitoring assesses whether a deployed system continues to have value in the form of benefit to clinicians, staff, and patients. Drawing on examples of deployed AI systems at their academic medical center, the authors provide practical guidance for creating monitoring plans based on these principles that specify which metrics to measure and at what cadence, who is responsible for acting when metrics change, and what concrete follow-up actions should be taken - for both traditional and generative AI. They also discuss challenges in implementing this framework, including the effort of monitoring for health systems with limited resources, and the difficulty of incorporating data-driven monitoring practices into complex organizations where conflicting priorities and definitions of success often coexist. This framework offers a starting point for health systems seeking to ensure that AI deployments remain safe and effective over time.

Indexed as

Artificial IntelligenceDelivery of Health CareHumansIntelligent Systems

Identifiers

PMID42418612

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.