ArticleScience advances2026
Implantable bioelectronic outlet.
Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Developing a reliable, long-term electrical interface for implanted bioelectronics is essential for chronic diagnostics, therapeutics, and device maintenance. Here, we introduce the implantable bioelectronic outlet (IBO), a soft, tissue-like electronic interface that enables on-demand, direct ohmic connection between implanted electronics and external devices. IBO is composed of a conducting polymer-coated low-density polymer matrix that is jacketed with a hydrophobic elastomer, allowing repetitive insertion of external electrical contacts without crack propagation. IBO was functional after 1 year of implantation with minimal tissue effects. We demonstrate that IBO enables high-fidelity, bidirectional transmission of signals and power, including low-voltage neurophysiological signals, high-speed digital signals, neurostimulation protocols, and efficient high-current power delivery, validated in small and large animal model studies. The IBO provides a robust and scalable platform for safe, direct, and durable electrical interfacing with implantable bioelectronics.
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