Evidence map›Paper›PMID 42418074›Full record

ArticleDigestive diseases and sciences2026

Risk Factors Associated with Recurrent Biliary Obstruction After Endoscopic Bilioduodenal Double Stenting.

Mitsuru Sugimoto, Tadayuki Takagi, Rei Suzuki, Hiroyuki Asama, Hiroshi Shimizu, Kentaro Sato, Kento Osawa, Rei Ohira, Jun Nakamura, Tsunetaka Kato and 4 more

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Article in Digestive diseases and sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Mitsuru SugimotoDepartment of Gastroenterology, School of Medicine, Fukushima Medical University, 1 Hikarigaoka, Fukushima City, Fukushima Prefecture, Fukushima, Japan. kita335@fmu.ac.jp.
Tadayuki TakagiDepartment of Gastroenterology, School of Medicine, Fukushima Medical University, 1 Hikarigaoka, Fukushima City, Fukushima Prefecture, Fukushima, Japan.
Rei SuzukiDepartment of Gastroenterology, School of Medicine, Fukushima Medical University, 1 Hikarigaoka, Fukushima City, Fukushima Prefecture, Fukushima, Japan.
Hiroyuki AsamaDepartment of Gastroenterology, School of Medicine, Fukushima Medical University, 1 Hikarigaoka, Fukushima City, Fukushima Prefecture, Fukushima, Japan.
Hiroshi ShimizuDepartment of Gastroenterology, School of Medicine, Fukushima Medical University, 1 Hikarigaoka, Fukushima City, Fukushima Prefecture, Fukushima, Japan.
Kentaro SatoDepartment of Gastroenterology, School of Medicine, Fukushima Medical University, 1 Hikarigaoka, Fukushima City, Fukushima Prefecture, Fukushima, Japan.
Kento OsawaDepartment of Gastroenterology, School of Medicine, Fukushima Medical University, 1 Hikarigaoka, Fukushima City, Fukushima Prefecture, Fukushima, Japan.
Rei OhiraDepartment of Gastroenterology, School of Medicine, Fukushima Medical University, 1 Hikarigaoka, Fukushima City, Fukushima Prefecture, Fukushima, Japan.
Jun NakamuraDepartment of Gastroenterology, School of Medicine, Fukushima Medical University, 1 Hikarigaoka, Fukushima City, Fukushima Prefecture, Fukushima, Japan.
Tsunetaka KatoDepartment of Gastroenterology, School of Medicine, Fukushima Medical University, 1 Hikarigaoka, Fukushima City, Fukushima Prefecture, Fukushima, Japan.
Takumi YanagitaDepartment of Gastroenterology, School of Medicine, Fukushima Medical University, 1 Hikarigaoka, Fukushima City, Fukushima Prefecture, Fukushima, Japan.
Mitsuru OtsukaDepartment of Gastroenterology, School of Medicine, Fukushima Medical University, 1 Hikarigaoka, Fukushima City, Fukushima Prefecture, Fukushima, Japan.
Takuto HikichiDepartment of Endoscopy, Fukushima Medical University Hospital, Hikarigaoka 1, Fukushima, Japan.
Hiromasa OhiraDepartment of Gastroenterology, School of Medicine, Fukushima Medical University, 1 Hikarigaoka, Fukushima City, Fukushima Prefecture, Fukushima, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEndoscopic bilioduodenal double stenting is sometimes necessary for patients with malignant bilioduodenal obstruction (MBDO). The patency of biliary stents is important for preventing cholangitis and continuing treatment. However, the factors that influence recurrent biliary obstruction (RBO) in patients with MBDO are not well known. This study aimed to identify the factors associated with RBO in patients who underwent endoscopic bilioduodenal double stenting.

methodsPatient characteristics, device use, and endoscopic treatment procedures were evaluated as possible risk factors for RBO.

resultsOverall, 55 patients with MBDO underwent endoscopic bilioduodenal double stenting (transpapillary drainage, n = 35; endoscopic ultrasound-guided biliary drainage, n = 20). Multivariate analysis using a Fine and Gray competing risk model revealed that biliary stenting on the oral side of the duodenal stricture (HR 2.98; 95% CI 1.16-7.68; p = 0.023) and chemotherapy (HR 3.74; 95% CI 1.25-11.22; p = 0.018) were significantly associated with RBO.

conclusionBiliary stenting on the oral side of the duodenal stricture was associated with RBO during duodenal stenting in patients with MBDO. Although chemotherapy was also associated with RBO in the multivariable competing risk analysis, this finding should be interpreted cautiously. Careful treatment selection, including consideration of gastrojejunostomy in patients with oral-side biliary stenting, may help reduce the incidence of RBO.

Indexed as

CholestasisStentsAgedAged, 80 and overDrainageFemaleHumansMaleMiddle AgedRecurrenceRetrospective StudiesRisk FactorsEndoscopic bilioduodenal double stentingERCP-guided biliary drainageEUS-guided biliary drainageTime to recurrent biliary obstruction

Identifiers

PMID42418074

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.