Evidence map›Paper›PMID 42417952›Full record

ArticleJournal of behavioral medicine2026

Goal disturbance and emotional symptoms in patients with cancer.

G Elise Doppenberg-Smit, Myra E van Linde, Femke Lamers, Annemarie M J Braamse, Rutger Koornstra, Evelien J M Kuip, Mariette Labots, Rune A W van de Wetering, Henk M W Verheul, Joost Dekker and 2 more

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Article in Journal of behavioral medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

12 authors.

G Elise Doppenberg-SmitDepartment of Psychiatry, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. g.e.doppenberg@amsterdamumc.nl.ORCID http://orcid.org/0009-0001-7567-1680
Myra E van LindeCancer Centre Amsterdam, Cancer Treatment and Quality of Life, Amsterdam, The Netherlands.
Femke LamersDepartment of Psychiatry, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0003-4344-5766
Annemarie M J BraamseAmsterdam Public Health, Mental Health Program, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0003-3216-6753
Rutger KoornstraDepartment of Medical Oncology, Rijnstate Hospital, Arnhem, The Netherlands.
Evelien J M KuipDepartment of Medical Oncology, Radboud Medical Center, Nijmegen, The Netherlands.
Mariette LabotsCancer Centre Amsterdam, Cancer Treatment and Quality of Life, Amsterdam, The Netherlands.
Rune A W van de WeteringDepartment of Medical Oncology, Slingeland Ziekenhuis, Doetinchem, The Netherlands.
Henk M W VerheulDepartment of Medical Oncology, Erasmus Medical Center, Rotterdam, The Netherlands.
Joost DekkerDepartment of Psychiatry, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0003-2027-0027
Adriaan W HoogendoornDepartment of Psychiatry, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Aartjan T F BeekmanDepartment of Psychiatry, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Funding

KWF Kankerbestrijding 11839
6 · The paper itself

Abstract

backgroundCancer is a major stressor leading to a wide range of emotions. Emotions, also negative emotions, are essentially adaptive, in the sense that they help patients cope with cancer. Emotions can also be maladaptive, if they are disproportionately severe or persistent, or interfere with functioning. Our overall goal was to explore whether disturbance of life goals provides a fruitful framework for developing indicators that can distinguish between adaptive and maladaptive emotions.

objectiveTo test the hypotheses that (1) goal disturbance and emotional symptoms are reciprocally and positively associated to each other; and (2) the association between goal disturbance and emotional symptoms is stronger in patients with maladaptive emotions as compared to patients with adaptive emotions.

methodsPatients with (non)metastasized disease who recently started systemic treatment (n = 132) filled out Ecological Momentary Assessments 5 times per day for 14 consecutive days in which emotional symptoms and activities related to life goals were documented. The importance of life goals in six domains was assessed with an interview (work/study, disease-related health, lifestyle health, social activities, religious, spiritual and intellectual activities, and leisure). Patients were grouped as having adaptive or maladaptive emotions based on a reference standard (a psychiatric diagnostic assessment, or the subjective need for professional mental healthcare). Linear mixed models were built in R, with either goal disturbance or negative emotional symptoms as dependent variable.

resultsGoal disturbance for social activities and leisure activities was significantly associated with more emotional symptoms. Goal disturbance for disease-related health activities was significantly associated with less emotional symptoms. No significant association was found for other activities (with one exception). With negative emotions as outcome variable, goal disturbance was more strongly associated with more emotional symptoms in patients with maladaptive emotions than patients with adaptive emotions for social, leisure and lifestyle health activities.

conclusionFurther research is warranted to develop an indicator of maladaptive emotions in patients with cancer based on the extent of goal disturbance of social, leisure and lifestyle health activities.

Indexed as

AdaptationCancerEmotional symptomsGoal disturbanceIndicator

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.