Evidence map›Paper›PMID 42417874›Full record

ArticleInternational urogynecology journal2026

Twelve Years of Managing Female Urogenital Fistula in Uganda: Characteristics, Repair Outcomes, and Predictors for Success in a Multicentre Cohort Study.

Musa Kayondo, Thomas Margolis, Onesmus Byamukama, Brenda Ainomugisha, Rogers Kajabwangu, Paul Kato Kalyebara, Leevan Tabaijuka, Henry Ochola, Henry Mark Lugobe, Verena Geissbühler

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Article in International urogynecology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

10 authors.

Musa KayondoDivision of Urogynecology and Female Pelvic Floor Medicine, Faculty of Medicine, Mbarara University of Science and Technology, P.O. Box 1410, Mbarara, Uganda. mkayondo@must.ac.ug.
Thomas MargolisDivision of Urogynecology and Female Pelvic Floor Medicine, Faculty of Medicine, Mbarara University of Science and Technology, P.O. Box 1410, Mbarara, Uganda.
Onesmus ByamukamaDivision of Urogynecology and Female Pelvic Floor Medicine, Faculty of Medicine, Mbarara University of Science and Technology, P.O. Box 1410, Mbarara, Uganda.
Brenda AinomugishaDivision of Urogynecology and Female Pelvic Floor Medicine, Faculty of Medicine, Mbarara University of Science and Technology, P.O. Box 1410, Mbarara, Uganda.
Rogers KajabwanguDivision of Urogynecology and Female Pelvic Floor Medicine, Faculty of Medicine, Mbarara University of Science and Technology, P.O. Box 1410, Mbarara, Uganda.
Paul Kato KalyebaraDivision of Urogynecology and Female Pelvic Floor Medicine, Faculty of Medicine, Mbarara University of Science and Technology, P.O. Box 1410, Mbarara, Uganda.
Leevan TabaijukaDivision of Urogynecology and Female Pelvic Floor Medicine, Faculty of Medicine, Mbarara University of Science and Technology, P.O. Box 1410, Mbarara, Uganda.
Henry OcholaDivision of Urogynecology and Female Pelvic Floor Medicine, Faculty of Medicine, Mbarara University of Science and Technology, P.O. Box 1410, Mbarara, Uganda.
Henry Mark LugobeDivision of Urogynecology and Female Pelvic Floor Medicine, Faculty of Medicine, Mbarara University of Science and Technology, P.O. Box 1410, Mbarara, Uganda.
Verena GeissbühlerUniversity Women's Clinic Basel, Spitalstrasse 21, 4056, Basel, Switzerland.

Funding

Else Kröner-Fresenius-Stiftung 2022_EKHA.111
6 · The paper itself

Abstract

introduction and hypothesisTo describe the characteristics and aetiology of urogenital fistula, and to determine the predictors for successful repair.

methodsWe conducted a multicentre retrospective cohort study using prospectively collected data of women who underwent urogenital fistula repair at four regional repair centres between 2010 and 2021. The fistulae were classified as ischaemic (urethrovaginal and vesicovaginal), iatrogenic (vesico-cervical, vesico-uterine, vaginal vault fistula, and ureteric fistula) and congenital. The patients were followed up at 3 months postoperatively to assess surgical outcomes. Successful repair was defined as fistula closure with urinary continence, while unsuccessful repair included failed fistula closure or residual urethral incontinence. Modified Poisson regression was used to estimate adjusted risk ratios (aRR) for predictors of successful repair.

resultsA total of 510 women were included. The mean age was 32.7 ± 12.5 years. The most common fistula type was urethrovaginal (34.9%). Successful repair was achieved in 80.8% (95% CI 77-84). Women with urethrovaginal fistula (aRR 0.18; 95% CI 0.1-0.4; p < 0.001), previous fistula repair (aRR 0.44; 95% CI 0.25-0.79; p = 0.005), and those who were divorced (aRR 0.47; 95 CI 0.27-0.83; p = 0.009) were less likely to have successful repair. In contrast, grand multiparity was associated with a higher likelihood of success (aRR 2.4; 95% CI 1.08-5.2; p = 0.03).

conclusionFistula repair outcomes were favourable, with a high success rate. Urethrovaginal fistula, previous repair, and divorce were associated with lower likelihood of success. These findings highlight the need for careful patient selection and specialised expertise in the management of complex fistulae.

Indexed as

Fistula repairGenitourinary fistulaObstetric fistulaSurgical outcomesUganda

Identifiers

PMID42417874

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