Evidence map›Paper›PMID 42417796›Full record

SynthesisRevista do Instituto de Medicina Tropical de Sao Paulo2026

The potential of essential oils as mosquito (Diptera: Culicidae) bio-repellents: a systematic review.

Adeilson Pimentel Rabelo, Rodrigo Alves Soares Cruz, Everson Dos Santos David, Erique da Costa Fonseca, Karen Carmo Dos Santos, Raimundo Nonato Picanço Souto

Abstract readSystematic Review
In one paragraph

Synthesis in Revista do Instituto de Medicina Tropical de Sao Paulo, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Adeilson Pimentel RabeloUniversidade Federal do Amapá, Laboratório de Arthropoda, Macapá, Amapá, Brazil.ORCID http://orcid.org/0000-0002-7014-1197
Rodrigo Alves Soares CruzUniversidade Federal do Amapá, Programa de Pós-Graduação em Ciências Farmacêuticas, Macapá, Amapá, Brazil.ORCID http://orcid.org/0000-0003-1728-4145
Everson Dos Santos DavidUniversidade Federal do Amapá, Laboratório de Arthropoda, Macapá, Amapá, Brazil.ORCID http://orcid.org/0000-0002-9636-9974
Erique da Costa FonsecaUniversidade Federal do Amapá, Laboratório de Arthropoda, Macapá, Amapá, Brazil.ORCID http://orcid.org/0000-0001-8906-5246
Karen Carmo Dos SantosUniversidade Federal do Amapá, Laboratório de Arthropoda, Macapá, Amapá, Brazil.ORCID http://orcid.org/0009-0000-8542-765X
Raimundo Nonato Picanço SoutoUniversidade Federal do Amapá, Laboratório de Arthropoda, Macapá, Amapá, Brazil.ORCID http://orcid.org/0000-0002-8795-1217

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Controlling culicid-borne diseases remains a global public health challenge. While public health actions are vital, individual protection via repellents is essential. Concerns regarding synthetic compounds such as DEET have intensified the search for sustainable plant-derived alternatives. This systematic review analyzed 33 experimental studies that were published from 2020 to 2024. A comprehensive search was performed on SciELO, PubMed, Scopus, Web of Science, ScienceDirect, and LILACS using the keywords "Repellency," "Essential Oils," and "Mosquitoes." Data were independently selected and extracted to evaluate protection time and repellency percentages. The included studies showed low risk of methodological bias according to SYRCLE. Results showed that most of the tested essential oils possess high protective potential. Species such as Perilla frutescens, Leucas stachydiformis, Cymbopogon nardus, and Eucalyptus camaldulensis achieved up to 100% repellency, with protection exceeding eight hours. The cage test was the predominant laboratory method. Essential oils are promising, effective alternatives to synthetic repellents, offering reduced environmental and toxicological impacts. However, this evidence is based on controlled laboratory conditions rather than field trials. This limitation may affect real-world effectiveness, and further research in natural environments is recommended to validate these results for commercial application.

Indexed as

CulicidaeInsect RepellentsOils, VolatilePlant OilsAnimalsInsect RepellentsOils, VolatilePlant Oils

Identifiers

PMID42417796
PMCPMC13336775

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.