Evidence map›Paper›PMID 42417783›Full record

ArticleArquivos brasileiros de cardiologia2026

Factors Associated With the High Prevalence of Metabolic Syndrome in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.

Marina Lamas Figueredo, Matheus Alves Amaral de Lima, Alexandre Moura Dos Santos, Samuel Katsuyuki Shinjo

Abstract read
In one paragraph

Article in Arquivos brasileiros de cardiologia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marina Lamas FigueredoDisciplina de Reumatologia, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, SP - Brasil.ORCID http://orcid.org/0009-0004-1041-0115
Matheus Alves Amaral de LimaDisciplina de Reumatologia, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, SP - Brasil.ORCID http://orcid.org/0009-0007-6784-3554
Alexandre Moura Dos SantosDisciplina de Reumatologia, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, SP - Brasil.
Samuel Katsuyuki ShinjoDisciplina de Reumatologia, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, SP - Brasil.ORCID http://orcid.org/0000-0002-3682-4517

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMetabolic syndrome (MetS) remains incompletely characterized in antineutrophil cytoplasmic antibody-associated vasculitis (AAV). This study aimed to determine the prevalence of MetS in patients with AAV and to identify factors associated with its presence.

methodsThis single-center, cross-sectional study included 62 patients with AAV (42 with granulomatosis with polyangiitis, 15 with eosinophilic granulomatosis with polyangiitis, and five with microscopic polyangiitis) who were under regular follow-up at a tertiary referral hospital. Patients were matched by age and sex with 53 controls. MetS was defined according to the National Cholesterol Education Program Adult Treatment Panel III criteria. Statistical significance was set at p < 0.05.

resultsThe median age of the patients was 56.1 years (interquartile range, 45.6-65.5); 53.2% were women, and 85.5% were White. The prevalence of MetS was significantly higher in the AAV group than in controls (43.5% vs 13.2%; p = 0.001). Diabetes mellitus, hypertension, and a family history of cardiovascular disease were more frequent among patients with AAV, whereas body mass index (BMI) and physical inactivity did not differ between groups. In multivariable analysis, MetS (odds ratio [OR], 4.52; 95%CI, 1.66-12.27; p = 0.003) and a family history of cardiovascular disease (OR, 3.81; 95%CI, 1.09-13.34; p < 0.05) were independently associated with AAV. Among patients with AAV, no differences were observed between those with and without MetS in terms of subtype of AAV, anthropometric measures, disease activity, family history, physical inactivity, or current treatment. In a multivariable analysis restricted to patients with AAV, MetS was independently associated with male sex (OR, 11.43; 95%CI, 2.81-46.52; p = 0.001) and higher BMI (OR, 1.13; 95%CI, 1.02-1.25; p = 0.022).

conclusionsMetS was highly prevalent among patients with AAV and was associated with male sex and higher BMI, contributing to an unfavorable cardiometabolic risk profile in this single-center cohort.

Indexed as

Anti-Neutrophil Cytoplasmic Antibody-Associated VasculitisMetabolic SyndromeAgedBody Mass IndexBrazilCase-Control StudiesCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceRisk Factors

Identifiers

PMID42417783
PMCPMC13398801

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.