ArticleClinical transplantation2026
Early Post-Kidney Transplant Treatment With Roxadustat Ameliorates Anemia and Reduces Blood Transfusion Needs in Inflamed Patients: A Case-Matched Study.
Article in Clinical transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
backgroundRoxadustat is an oral hypoxia-inducible factor prolyl-hydroxylase inhibitor. Recent studies have shown no inferiority of roxadustat compared to erythropoietin in chronic kidney disease and in post-transplant patients. We evaluated roxadustat versus erythropoiesis-stimulating agents (ESAs) in very early posttransplant patients.
methodsWe performed a retrospective analysis of the clinical course and laboratory changes in posttransplant patients treated with roxadustat (16 patients) or a high-dose erythropoiesis-stimulating agent (ESA) (16 patients) for anemia between March and September 2025. We compared haemoglobin, creatinine, lipid levels, and iron status. The therapy was started after the kidney transplant, respectively, after a median of 3.5 and two days. Every patient was followed up at two weeks, one month, two months, and three months.
resultsPatients treated with roxadustat showed a significantly greater and faster increase in Hb levels at 2 weeks (p = 0.047) than the ESA group. After 2 weeks, we observed a significant difference in the need for blood transfusions between the groups (p = 0.029; 18.8% in the roxadustat group vs. 62.5% in the ESA group). No significant differences were observed in iron or inflammation status during the study. The roxadustat group achieved a significantly better lipid profile after one month (p < 0.05 for cholesterol and LDL). During the follow-up, no adverse events related to roxadustat were reported.
conclusionAdministration of oral roxadustat in very early post-transplant patients is effective and safe, rapidly improving anemia and reducing the need for transfusions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.