Evidence map›Paper›PMID 42416933›Full record

ArticleCureus2026

Clinicoepidemiological and Dermoscopic Patterns of Hypopigmented Disorders: A Cross-Sectional Observational Study.

Jithin Jayaraj, Yogesh Devaraj, Mukunda R Swaroop, Jagath Jayaraj, Shreya Rangaswamy, Jayaprakash Mh, Akshatha V Reddy, Shifali Harinath

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Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jithin JayarajDermatology, Adichunchanagiri Institute of Medical Sciences, Adichunchanagiri University, Mandya, IND.
Yogesh DevarajDermatology, Adichunchanagiri Institute of Medical Sciences, Adichunchanagiri University, Mandya, IND.
Mukunda R SwaroopDermatology, Akash Institute of Medical Sciences, Bangalore, IND.
Jagath JayarajDermatology, Great Western Hospitals NHS Foundation Trust, Swindon, GBR.
Shreya RangaswamyDermatology, Adichunchanagiri Institute of Medical Sciences, Adichunchanagiri University, Mandya, IND.
Jayaprakash MhDermatology, Adichunchanagiri Institute of Medical Sciences, Adichunchanagiri University, Mandya, IND.
Akshatha V ReddyDermatology, Adichunchanagiri Institute of Medical Sciences, Adichunchanagiri University, Mandya, IND.
Shifali HarinathDermatology, Adichunchanagiri Institute of Medical Sciences, Adichunchanagiri University, Mandya, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Hypopigmented disorders comprise a heterogeneous group of dermatoses characterized by hypopigmented macules, patches, plaques, papules, and scaling lesions. These disorders often follow a chronic course and significantly affect patients' quality of life. Clinical differentiation may be challenging because of overlapping clinical presentations and atypical morphology. Dermoscopy serves as a non-invasive diagnostic tool that enhances visualization of submacroscopic morphological features and improves diagnostic accuracy. Materials and methods This cross-sectional observational study included 150 patients with hypopigmented disorders attending the dermatology outpatient department over a period of 18 months. The study population comprised 84 (56%) females and 66 (44%) males, with a mean age of 30.2 ± 2.57 years. Patients fulfilling the inclusion and exclusion criteria were enrolled after obtaining informed consent and institutional ethics committee's approval. Detailed history taking and clinical examination were performed using a predesigned proforma. Dermoscopic evaluation was conducted using polarized and non-polarized modes at 10× magnification. Clinical and dermoscopic findings were documented photographically and analyzed. Results Among 150 patients, pityriasis versicolor was the most common disorder, observed in 36 (24%) patients, followed by vitiligo in 33 (22%) patients and pityriasis alba in 30 (20%) patients. Reduced pigment network was the most consistent dermoscopic finding and was observed in all 150 (100%) cases. Scaling was predominantly observed in pityriasis versicolor in 25 (69.4%) patients and pityriasis alba in 18 (60%) patients. Vascular structures were commonly observed in lichen sclerosus in nine (90%) patients, while leukotrichia was characteristic of vitiligo and was seen in 13 (39.4%) patients. Additional findings such as pseudopod-like extensions, perifollicular pigmentation, comet-tail appearance, and double-edged scales assisted in differentiating specific disorders. Dermoscopic findings showed a strong correlation with clinical diagnosis. Conclusion Dermoscopy is a reliable and non-invasive adjunctive tool in the evaluation of hypopigmented disorders. In addition to a reduced pigment network, characteristic findings such as scaling patterns, vascular morphology, follicular changes, and border alterations improve diagnostic precision and help distinguish clinically similar conditions. Incorporation of dermoscopy into routine dermatological practice enhances diagnostic confidence and may reduce the need for invasive procedures.

Indexed as

dermoscopyhypopigmented disordersidiopathic guttate hypomelanosispityriasis versicolorvitiligo

Identifiers

PMID42416933
PMCPMC13339883

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