ReviewRSC advances2026
Recent advances in azo-based probes for analyte sensing: molecular nanoarchitectonics and advanced applications.
Review in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review examines recent advancements (2016-2025) in azo-based chemosensors for detecting metal ions, anions, and small molecules. A total of 52 structurally diverse probes were analysed and categorised into single-analyte and multi-analyte systems and assessed using a designed scoring framework across four dimensions: aqueous compatibility, selectivity rigor, real-sample validation, and deployment readiness. The field has evolved from simple colorimetric dyes in organic media to scaffolds incorporating heterocyclic receptors, rhodamine spirolactams, and displacement assays, achieving nanomolar detection limits and validation in real environmental and biological matrices. Model studies, such as sensors 3 and 4 (which contain water-solubilising moieties) and sensor 44 (a commercial dye-based indicator displacement probe), set standards for rigour and translational potential. However, persistent limitations hinder widespread utility: over 70% of sensors depend on organic co-solvents, interference studies are often incomplete, real-sample validation is insufficient, and synthetically complex designs impede scalability. Future directions, including water-compatible designs, displacement assays, reusable solid-state platforms, and the repurposing of commercial dyes, offer a pathway to transform proof-of-concept into field-deployable, sustainable sensing solutions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.