Evidence map›Paper›PMID 42416715›Full record

ArticleRSC advances2026

An effective photothermally active titanium-copper nanocomposite for breast cancer therapy.

Laleh Salarilak, Abolfazl Doosti, Mehdi Haddad, Ali Kalantari-Hesari, Faezeh Almasi, Farnaz Eslami, Kiana Nazari Nasi, Mir-Jamal Hosseini, Aziz Maleki

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laleh SalarilakZanjan Pharmaceutical Nanotechnology Research Center (ZPNRC), Zanjan University of Medical Sciences Zanjan 45139-56184 Iran.
Abolfazl DoostiDepartment of Pharmaceutical Nanotechnology, School of Pharmacy, Zanjan University of Medical Sciences Zanjan 45139-56184 Iran maleki@zums.ac.ir.
Mehdi HaddadStudent Research Committee, School of Pharmacy, Zanjan University of Medical Sciences Zanjan 45139-56184 Iran.
Ali Kalantari-HesariDepartment of Basic Sciences, Faculty of Veterinary Medicine, Bu-Ali Sina University Hamedan Iran.
Faezeh AlmasiZanjan Pharmaceutical Nanotechnology Research Center (ZPNRC), Zanjan University of Medical Sciences Zanjan 45139-56184 Iran.
Farnaz EslamiZanjan Pharmaceutical Nanotechnology Research Center (ZPNRC), Zanjan University of Medical Sciences Zanjan 45139-56184 Iran.
Kiana Nazari NasiStudent Research Committee, School of Pharmacy, Zanjan University of Medical Sciences Zanjan 45139-56184 Iran.
Mir-Jamal HosseiniZanjan Applied Pharmacology Research Center, Health and Metabolic Diseases Research Institute, Zanjan University of Medical Sciences Zanjan Iran jamal_hossini@yahoo.com.ORCID https://orcid.org/0000-0002-4469-9488
Aziz MalekiZanjan Pharmaceutical Nanotechnology Research Center (ZPNRC), Zanjan University of Medical Sciences Zanjan 45139-56184 Iran.ORCID https://orcid.org/0000-0003-3203-7492

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer therapy faces several challenges including metastasis, subsequent recurrence and the high susceptibility of immunocompromised patients to secondary bacterial infections. In this study, a copper-doped titanium dioxide nanocomposite (Ti-Cu NC) was developed as a multifunctional photothermal agent for breast cancer treatment. In 4T1 murine breast cancer cells, Ti-Cu NCs induced significant (approximately 3.8-fold increase compared to control) reactive oxygen species (ROS) production, leading to apoptosis and cell death with a synergistic effect observed upon near-infrared (NIR) irradiation (1.5 W cm

Identifiers

PMID42416715
PMCPMC13339989

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.