ArticleReviews in cardiovascular medicine2026
Changes in Cardiac-Arterial Coupling After Cardiac Surgery for Aortic Valve Disease.
Article in Reviews in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Aortic valve disease affects vascular and cardiac remodeling and function, with changes observed after cardiac surgery. Ventricular-arterial coupling (VAC), which reflects the interaction between the left ventricle and the arterial system, may be altered by aortic valve replacement (AVR). Therefore, this study aimed to determine changes in VAC and atrial-arterial coupling (AAC) in patients with aortic valve disease before and after AVR. Methods: A total of 41 patients (median age 67 years, interquartile range (IQR) 62-71) undergoing AVR, including 24 (58.5%) with aortic stenosis (AS), were evaluated before and early (3 days) after cardiac surgery. Left atrial reservoir strain (LARS) and left ventricular (LV) global longitudinal strain (GLS) were assessed by echocardiography. Carotid-femoral pulse wave velocity (cfPWV), brachial-ankle-PWV (baPWV), and cardio-ankle vascular index (CAVI) were measured. VAC and AAC were defined as ratios of arterial stiffness to cardiac strain (CAVI/GLS, CAVI/LARS, baPWV/GLS, baPWV/LARS, cfPWV/GLS, cfPWV/LARS). Results: Atrial and ventricular strain and arterial stiffness significantly worsened after surgery. Ventricular-arterial uncoupling was reflected by a substantial increase in arterial stiffness to LV strain ratios ( Conclusions: Worsened ventricular-arterial uncoupling can be detected early after cardiac surgery using novel measures of VAC, including ratios of peripheral arterial stiffness to cardiac deformation. This study extends these findings by demonstrating atrial-arterial uncoupling, suggesting a generalized cardiac-arterial uncoupling after valve surgery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.