ArticleReviews in cardiovascular medicine2026
Predictors for Improvement of Mitral Regurgitation in Patients With Pure Severe Aortic Regurgitation Undergoing Transcatheter Aortic Valve Replacement: Can We Kill Two Birds With One Stone?
Article in Reviews in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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8 authors.
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Abstract
Background: Transcatheter aortic valve replacement (TAVR) is now recognized as an important treatment for pure severe aortic regurgitation (PSAR). Some patients with PSAR also suffer from functional mitral regurgitation (FMR). However, whether TAVR can improve FMR in patients with PSAR and the predictors of this improvement remain unknown. Thus, this study aimed to explore predictors of FMR improvement in patients with PSAR undergoing TAVR. Methods: Patients with PSAR and ≥mild FMR who underwent TAVR at the Zhongshan Hospital Affiliated with Fudan University were enrolled from June 2020 to June 2024. Participants were divided into groups with or without FMR improvement depending on whether FMR improved 1 month post-TAVR. Baseline data, imaging results, and follow-up data of the patients were collected. Result: This study included 111 patients, among whom 59 had improved FMR, and 52 did not. Compared to patients without FMR improvement, significantly fewer patients in the FMR-improved group were diagnosed with renal insufficiency (0% vs. 10%; Conclusion: FMR improvement is observed in approximately half of PSAR patients undergoing TAVR. Higher FMR, lower LVEF, and hypertension before a TAVR are independent predictors of improvement in FMR.
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