Evidence map›Paper›PMID 42416527›Full record

ArticleEuropean heart journal. Imaging methods and practice2026

ΔVExPLUs: prognostic value of integrating serial changes in VExUS score and lung ultrasound in acute decompensated heart failure.

Gustavo Paes Silvano, Marina Petersen Saadi, Henrique Cabral Scherer, Guilherme Pinheiro Machado, Renato Ferraz Almeida, Kaleb Pinto Spannenberger, Fernando Luis Scolari, Andreia Biolo, Luis Eduardo Paim Rohde, Hatem Soliman Aboumarie and 2 more

Abstract read
In one paragraph

Article in European heart journal. Imaging methods and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Gustavo Paes SilvanoPostgraduate Program in Cardiology and Cardiovascular Sciences, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos Street, 2400-2nd Floor, Porto Alegre, RS 90035-003, Brazil.ORCID https://orcid.org/0000-0001-7264-8277
Marina Petersen SaadiCardiology Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.
Henrique Cabral SchererCardiology Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.
Guilherme Pinheiro MachadoCardiology Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.
Renato Ferraz AlmeidaSchool of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Kaleb Pinto SpannenbergerCardiology Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.
Fernando Luis ScolariCardiology Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.
Andreia BioloPostgraduate Program in Cardiology and Cardiovascular Sciences, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos Street, 2400-2nd Floor, Porto Alegre, RS 90035-003, Brazil.
Luis Eduardo Paim RohdePostgraduate Program in Cardiology and Cardiovascular Sciences, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos Street, 2400-2nd Floor, Porto Alegre, RS 90035-003, Brazil.
Hatem Soliman AboumarieDepartment of Anaesthetics and Critical Care, Harefield Hospital, Royal Brompton and Harefield Hospitals, London, United Kingdom; School of Cardiovascular, Metabolic Medicine and Sciences, King's College London, London, United Kingdom.
Guilherme Heiden TeloCardiology Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.
Anderson Donelli da SilveiraPostgraduate Program in Cardiology and Cardiovascular Sciences, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos Street, 2400-2nd Floor, Porto Alegre, RS 90035-003, Brazil.ORCID https://orcid.org/0000-0002-0327-3392

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: To investigate whether early combined changes in venous excess ultrasound (VExUS) and lung ultrasound (LUS) were associated with outcomes in acute decompensated heart failure (ADHF). Methods and results: We prospectively enrolled 104 patients with ADHF [mean age 64.3 ± 13.5 years, 69.2% male, median left ventricle ejection fraction 24.5% (18.0, 32.0)]. VExUS score and LUS were performed within 24 h of admission and after 72 h. Changes in congestion were integrated into a single metric (ΔVExPLUs = [2 × ΔVExUS] + ΔLUS), with ΔVExUS multiplied by two to balance its narrower scoring range. The primary outcome was in-hospital mortality. Secondary outcomes included 30-day all-cause mortality and a composite of 30-day all-cause mortality, heart transplantation and left ventricular assist device implantation. Patients with greater ΔVExPLUs improvement had lower rates of in-hospital mortality (3% vs. 46%; Conclusion: Serial integration of systemic and pulmonary ultrasound parameters through ΔVExPLUs is independently associated with short-term outcomes in ADHF and may improve early risk stratification.

Indexed as

acute decompensated heart failurelung ultrasoundpoint-of-care ultrasoundpulmonary congestionrisk stratificationVExUS score

Identifiers

PMID42416527
PMCPMC13339954

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.