ArticleJournal of anesthesia and translational medicine2026
Acute cerebral infarction caused by severe anaphylactic shock: A case report.
Article in Journal of anesthesia and translational medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Perioperative anaphylactic reactions, especially those induced by colloid solutions like gelatins, can lead to severe hypotension and tissue hypoperfusion, with potential serious complications. Case Presentation: We present a rare case of acute cerebral infarction following severe anaphylaxis during sinus lesion resection under general anesthesia. A 16-year-old patient received succinylated gelatin for hypovolemia. Within 7 min, the patient developed profound hypotension (45/25 mmHg), tachycardia (139 bpm), and severe desaturation (63%), necessitating treatment with epinephrine and 35 min of continuous resuscitation Postoperatively, the patient developed headache and memory deficits, prompting an MRI that revealed an acute infarction. Follow-up MRI on postoperative day 27 showed significant lesion resolution accompanied by improvement in neurological symptoms. Conclusions: This case highlights cerebral ischemia as a potential sequela of anaphylaxis-induced hypotension, emphasizing prompt hemodynamic stabilization and neurologic vigilance in perioperative hypersensitivity reactions.
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