Evidence map›Paper›PMID 42416423›Full record

ArticleInternational journal of surgery case reports2026

Reconstruction of a rare case of bilateral juvenile gigantomastia at a tertiary hospital: a case report.

Edouard K Rugendabanga, Gauthier B Murhula, Laura Pompermaier

Abstract readCase Reports
In one paragraph

Article in International journal of surgery case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Edouard K RugendabangaDepartment of Surgery, Plastic Surgery and Burn Unit, Muhimbili National Hospital, Dar-Es-Salaam, Tanzania.ORCID https://orcid.org/0009-0002-8044-7111
Gauthier B MurhulaDepartment of Surgery, Plastic Surgery and Burn Unit, Muhimbili National Hospital, Dar-Es-Salaam, Tanzania.
Laura PompermaierDepartment of Biomedical and Clinical Sciences, Centre for Teaching & Research in Disaster Medicine and Traumatology (KMC), Linköping University, Linköping, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Juvenile gigantomastia is a rare benign breast pathology that predominantly affects adolescents and women younger than 18 years of age. It is characterized by excessive, diffuse enlargement of the breast tissue (more than 1.5-2.5 kg per breast or constituting over 3% of total body weight), involving both glandular and stromal components. The histological picture consists of a juvenile fibroadenoma (JFA), which represents a distinct subtype of fibroepithelial breast tumor. The condition can cause severe physical discomfort, pain, posture abnormalities, recurrent skin infections, difficulties with mobility and personal hygiene, low self-esteem, and social stigma. Case presentation: A 15-year-old female presented with a 1-year history of progressive bilateral breast enlargement without nipple discharge, systemic symptoms, or trauma. On local examination, the breasts were grossly enlarged, soft, and non-tender on palpation, with the skin overstretched and visible ulcerations. Modified Goldilocks reduction mammoplasty was performed after excluding other pathologies through a breast ultrasound and hormonology report. Histology reported JFA. Discussion: JFA is a rare form of benign breast tumor, which manifests during puberty and leads to excessive breast development (gigantomastia) and its related discomfort. It is hypothesized that the causes are due to hypersensitivity of breast tissue to normal circulating estrogens, and hormonal therapy has been reported as a possible treatment, but surgery is considered the definitive treatment. Counseling on follow-up plans should be done to detect complications and recurrence. Conclusion: JFA patients seek care for physical disability and psychological distress. Surgical intervention is the definitive treatment, and histology confirms the diagnosis.

Indexed as

case-reportgigantomastiamodified Goldilocksreduction mammoplasty

Identifiers

PMID42416423
PMCPMC13340718

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.