Evidence map›Paper›PMID 42416311›Full record

Trial reportFrontiers in oral health2026

WeCare oral kit outperforms artificial saliva in salivary flow and oral health.

Leticia Mello Bezinelli, Marcella Ferreira Gobbi, Gabriela Vitoria Carvalho Campos, Jéssica Andrade-Silva, Vitor Ulisses Monnaka, Fernanda de Paula Eduardo

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Frontiers in oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07555444 (Evaluation of an Oral Care Kit for Maintaining the Oral Health of Patients Admitted to the Intensive Care Unit), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07555444 nacompletednot on this map

Evaluation of an Oral Care Kit for Maintaining the Oral Health of Patients Admitted to the Intensive Care Unit

TypeinterventionalSponsorHospital Israelita Albert EinsteinRan2022 to 2025Enrolled82ConditionsXerostomia, HyposalivationArmsOral Care Kit, Artificial Saliva
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Leticia Mello BezinelliHospital Israelita Albert Einstein, São Paulo, Brazil.
Marcella Ferreira GobbiFaculdade de Odontologia, Universidade de São Paulo, São Paulo, Brazil.
Gabriela Vitoria Carvalho CamposFaculdade Israelita de Ciências da Saúde Albert Einstein, São Paulo, Brazil.
Jéssica Andrade-SilvaDepartment of Innovation, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Vitor Ulisses MonnakaDepartment of Innovation, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Fernanda de Paula EduardoHospital Israelita Albert Einstein, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Critically ill patients frequently develop xerostomia and hyposalivation due to clinical instability and medical interventions. These conditions impair oral health, increase discomfort, and may contribute to infectious complications. Although artificial saliva is commonly used to reduce oral dryness, no standardized oral care strategy has been established for this population. Aims: To compare the effectiveness of a structured oral care intervention (WeCare oral care kit) with artificial saliva in improving salivary function, oral health, and oral comfort in patients hospitalized in intensive care and step-down units. Methods: This randomized clinical trial included 82 patients allocated to the WeCare group ( Results: The artificial saliva group demonstrated limited benefits, with significant improvements only in oral dryness ( Conclusions: The WeCare oral care kit provided broader and more consistent clinical benefits than artificial saliva, demonstrating superior effectiveness in improving salivary function, oral health, and patient-reported oral comfort. Clinical Trial Registration: ClinicalTrials.gov, NCT07555444, https://clinicaltrials.gov/study/NCT07555444.

Indexed as

artificial salivaintensive care unitsoral hygienesalivationxerostomia

Identifiers

PMID42416311
PMCPMC13337760

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.