Evidence map›Paper›PMID 42416263›Full record

ArticleTransplantation direct2026

Optimizing Kidney Allograft Years: Underutilization of Pediatric Donors.

Nicholas S Herrera, Ana Cortez, Diane M Cibrik, Bradley A Warady

Abstract read
In one paragraph

Article in Transplantation direct, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nicholas S HerreraDivision of Nephrology, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS.ORCID https://orcid.org/0009-0003-4559-237X
Ana CortezDivision of Nephrology, Department of Pediatrics, Children's Mercy Kansas City, Kansas City, MO.ORCID https://orcid.org/0009-0002-5547-4564
Diane M CibrikDivision of Nephrology, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS.ORCID https://orcid.org/0009-0007-7631-4195
Bradley A WaradyDivision of Nephrology, Department of Pediatrics, Children's Mercy Kansas City, Kansas City, MO.ORCID https://orcid.org/0000-0003-1812-6587

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The Kidney Donor Profile Index (KDPI) score drives kidney allocation in the United States for both adult and pediatric donors, despite the calculation being primarily derived from adult donor data. A KDPI of ≤20% is considered to have the longest graft survival potential and is typically prioritized for recipients who have a low Estimated Posttransplant Survival (EPTS) score. Using KDPI to assess pediatric donor quality may underestimate graft survival and result in underutilization of these kidneys for recipients with a low EPTS score. Methods: Using Scientific Registry of Transplant Recipients data, we analyzed 5-y posttransplant death-censored graft survival of kidneys from donors aged 0-<4, 4-<8, 8-<12, and 12-<18 y compared with adult donor kidneys with a KDPI of ≤20% to adult recipients using Kaplan-Meier analysis, pairwise comparisons, and multivariate Cox proportional models. Results: Death-censored graft survival was not significantly different for pediatric donors aged 8-<12 y (χ Conclusions: Graft survival for kidneys from donors aged 8-18 y is not inferior to that of adult donors with a KDPI of ≤20%. These data support the use of pediatric donors aged 8 y and older for those recipients who traditionally received adult donor kidneys with a KDPI of ≤20%.

Identifiers

PMID42416263
PMCPMC13340697

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.